An eleven-year retrospective hospital-based study of epidemiological data regarding human strongyloidiasis in northeast Thailand

BMC Infectious Diseases

Research Article

Wanida Kanarkard¹  Thidarat K. Prasongdee²  Porntip Laummaunwai²  Sureeporn Naonongwai²  Kraisit Sathapornworachai²  Oranuch Sanpool³  Wanchai Maleewong³  Pewpan M. Intapan³  Pokkamol Laoraksawong⁴  Ratthaphol Kraiklang⁴ 

[1] Department of Computer Engineering, Faculty of Engineering, Khon Kaen University, Khon Kaen, Thailand;Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;Department of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand;Research and Diagnostic Center for Emerging Infectious Diseases, Mekong Health Science Institute, Khon Kaen University, Khon Kaen, Thailand;Department of Public Health Administration, Health Promotion, Nutrition, Faculty of Public Health, Khon Kaen University, Khon Kaen, Thailand;

关键词: Prevalence;    Strongyloidiasis;    Hospital-based study;    Thailand;   

DOI  :  10.1186/s12879-017-2723-z

 received in 2017-02-08, accepted in 2017-09-08,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundHuman strongyloidiasis is a chronic and persistent gastrointestinal disease caused by infection with soil-transmitted helminths of the genus Strongyloides. The aim of this research was to obtain diagnostic prevalence regarding strongyloidiasis in northeast Thailand through a hospital-based study.MethodsPatients’ demographic data and the results of stool examinations conducted using the formalin ethyl acetate concentration technique were collected from the parasitology laboratory records at Srinagarind Hospital in Khon Kaen, Thailand. The relevant information from years 2004 to 2014 was collected and descriptively analyzed.ResultsOf a total of 22,338 patients, 3889 (17.4%) had stool samples that tested positive for Strongyloides larvae. The highest prevalence was 22.8% (95% CI = 19.6–26.2%) in the year 2004. This percentage progressively decreased, reaching 11.2% (95% CI = 10.2–12.4%) in 2013 and remaining stable at 12.9% (95% CI = 11.8–14.1%) in 2014. Males (2741 cases) had double the positivity rate of females (1148 cases). The prevalence of infection was highest (25.9%; 95% CI = 24.5–27.3%) among patients that were 51–60 years of age.ConclusionsAreas endemic for strongyloidiasis should be emphasized under the national helminth control program and health education campaigns. Nationwide assessments should also be performed regarding Strongyloides infection, including risk factors, treatment, and prevention. The diagnostic laboratory data presented here identify the geographical focus of disease to be the northeastern region of the country. Further targeted surveillance using more sensitive methods will almost certainly reveal a higher individual disease burden than found in this report.

【 授权许可】

CC BY   
© The Author(s). 2017