Bilateral interstitial keratitis following COVID-19: a case report

BMC Ophthalmology

Case Report

Nathalie Dalloul Daher¹  Zeba A. Syed¹ 

[1] Cornea Service, Wills Eye Hospital, Sidney Kimmel Medical College at Thomas Jefferson University, 840 Walnut Street, Suite 920, 19107, Philadelphia, PA, USA;

关键词: Interstitial keratitis;    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2);    COVID-19;   

DOI  :  10.1186/s12886-023-03160-4

 received in 2023-03-19, accepted in 2023-10-02,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundAlthough the primary target of severe acute respiratory syndrome coronavirus 2 is the respiratory tract, the expression of the angiotensin-converting enzyme 2 receptor in other tissues facilitates viral entry in others parts of the body, including ocular structures. Ocular manifestations may occur before, during, or after systemic infection.Case presentationWe report the case of a 60-year-old male who presented with bilateral interstitial keratitis after the onset of COVID-19, with ocular symptoms starting within 7 days after systemic symptoms. Laboratory investigation did not identify any alternative etiology for his disease, although the possibility of Epstein-Barr virus or herpes simpex virus could not be definitively ruled out. The patient had already developed significant corneal scarring and visual debilitation by the time topical steroids were initiated, and his final corrected visual acuity with rigid gas permeable contact lenses was 20/50 and 20/80 in the right and left eye, respectively.ConclusionsThe involvement of ocular tissue by the virus can lead to permanent sequelae such as severe visual loss, and clinicians should be aware of and recognize ophthalmic manifestations of this disease to prompt early intervention.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

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