Prevalence of Borrelia burgdorferi sensu lato in rodents from Gansu, northwestern China

BMC Microbiology

Research Article

Jijun Zhang¹  Zengjia Liu¹  Fang Zhang¹  Zhanwei Gong¹ 

[1] The Center for Disease Control and Prevention of Lanzhou Command, PLA, 509 Dong-Gang Dong Road, 730020, Chenguan District, Lanzhou, PR China;

关键词: Lyme Disease;    Gansu Province;    Rodent Species;    Borrelia Burgdorferi;    Reservoir Host;   

DOI  :  10.1186/1471-2180-10-157

 received in 2009-07-12, accepted in 2010-05-28,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundLyme disease is a multi-organ infection disease caused by Borrelia burgdorferi sensu lato. Lyme disease was first documented in north-east China in 1986. Since then more than 20 provinces in China were confirmed the existence of nature foci of Lyme disease. In the present study, a molecular epidemiological survey was conducted to investigate the presence of Borrelia burgdorferi sensu lato in rodents from Gansu Province for the first time.ResultA total of 140 rodents of 7 species were examined for Borrelia burgdorferi sensu lato. by nested-PCR and culture isolation. The overall infection rate was 22.86%. Two rodent species most frequently trapped were responsible for all positive. 3 strains were isolated from Apodemus agrarius, which belonged to B. garinii, 1 strain isolated from Rattus losea was identified as B. afzelii.ConclusionThe study firstly showed the role of rodents in maintaining the pathogen of Lyme disease in the environment from Gansu Province and there existed at least two genotypes of Lyme disease spirochaetes in rodents.

【 授权许可】

Unknown   
© Zhang et al; licensee BioMed Central Ltd. 2010. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.