Cardiac T1 Mapping and Extracellular Volume (ECV) in clinical practice: a comprehensive review

Journal of Cardiovascular Magnetic Resonance

Review

Daniel R. Messroghli¹  David A. Broadbent²  Pankaj Garg²  Sven Plein²  John P. Greenwood²  Philip Haaf³ 

[1] Department of Internal Medicine – Cardiology, German Heart Institute Berlin, Berlin, Germany;Division of Biomedical Imaging, Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, LS2 9JT, Leeds, UK;Division of Biomedical Imaging, Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, LS2 9JT, Leeds, UK;Department of Cardiology and Cardiovascular Research Institute Basel (CRIB), University Hospital Basel, Petersgraben 4, 4054, Basel, Switzerland;

关键词: T1 mapping;    ECV;    Cardiomyopathy;    Acute chest pain syndromes;    Diffuse myocardial fibrosis;   

DOI  :  10.1186/s12968-016-0308-4

 received in 2016-08-06, accepted in 2016-11-15,  发布年份 2016

来源: Springer

【 摘 要 】

Cardiovascular Magnetic Resonance is increasingly used to differentiate the aetiology of cardiomyopathies. Late Gadolinium Enhancement (LGE) is the reference standard for non-invasive imaging of myocardial scar and focal fibrosis and is valuable in the differential diagnosis of ischaemic versus non-ischaemic cardiomyopathy. Diffuse fibrosis may go undetected on LGE imaging. Tissue characterisation with parametric mapping methods has the potential to detect and quantify both focal and diffuse alterations in myocardial structure not assessable by LGE. Native and post-contrast T1 mapping in particular has shown promise as a novel biomarker to support diagnostic, therapeutic and prognostic decision making in ischaemic and non-ischaemic cardiomyopathies as well as in patients with acute chest pain syndromes. Furthermore, changes in the myocardium over time may be assessed longitudinally with this non-invasive tissue characterisation method.

【 授权许可】

CC BY   
© The Author(s). 2016