Irritable bowel syndrome-specific health-related quality of life instrument: development and psychometric evaluation

Health and Quality of Life Outcomes

Research

Oran Kwon¹  Yoon Jae Kim²  Jung Ho Kim²  Jin Il Kim³  Dae Young Cheung³  Ki Baik Hahm⁴  WonHee Kim⁴  Jong-Jae Park⁵  Moon Kyung Joo⁵  Eun-Hyun Lee⁶ 

[1] Department of Food & Nutritional Sciences, Ewha Womans University, Seoul, Republic of Korea;Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, Republic of Korea;Department of Internal Medicine, The Catholic University of Korea, Yeouido St. Mary’s Hospital, Seoul, Republic of Korea;Digestive Disease Center, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea;Division of Gastroenterology, Department of Internal Medicine, Korea University Guro Hospital, Seoul, Republic of Korea;Graduate School of Public Health, Ajou University, 164 Worldcup-ro, Yeongtong-gu, 443-380, Suwon-si, Gyeonggi-do, Republic of Korea;

关键词: Irritable bowel syndrome;    Health-related quality of life;    Reliability;    Validity;   

DOI  :  10.1186/s12955-016-0423-9

 received in 2015-06-03, accepted in 2016-02-04,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundHealth-related quality of life (HRQOL) is an important outcome indicator for chronic disease, and particularly in the absence of biological markers for illness, such as with irritable bowel syndrome (IBS). The aims of this study were to develop and evaluate a new IBS-specific HRQOL instrument (IBS-HR-QOL).MethodsThis methodological study comprised three steps: conceptualization of the IBS-HR-QOL, item extraction and establishment of content validity, and psychometric evaluation of the instrument with 267 IBS patients recruited from four university hospitals.ResultsThe content validity of the developed IBS-HR-QOL was assessed by 11 experts. Exploratory and confirmatory factor analyses yielded four factors. The criterion and convergent validities of the IBS-HR-QOL were demonstrated using the Short Form-36 and the Hospital Anxiety and Depression Scale, respectively. Known-groups validity was demonstrated using a symptom-severity scale. The internal consistency reliability and test-retest reliability were satisfactory, with a Cronbach’s alpha and intraclass correlation coefficient of 0.93 and 0.88, respectively.ConclusionsThe IBS-HR-QOL comprises a total of 16 items. The IBS-HR-QOL demonstrated good psychometric properties. This instrument is easily comprehensible and short, rendering it feasible for use in clinical practice and research.

【 授权许可】

CC BY   
© Lee et al. 2016