Aggregatibacter actinomycetemcomitans osteomyelitis in a 12 year old boy: case report emphasizing the importance of tissue culture, and review of literature

Annals of Clinical Microbiology and Antimicrobials

Case Report

Iain Gosbell¹  John S. Whitehall²  Ketaki Sharma²  Poonam Mudgil² 

[1] Department of Infectious Diseases and Microbiology, School of Medicine, Western Sydney University, Sydney, NSW, Australia;Department of Paediatrics, School of Medicine, Western Sydney University, Sydney, NSW, Australia;

关键词: Osteomyelitis;    Colistin;    Gingival Crevicular Fluid;    Chronic Osteomyelitis;    Flucloxacillin;   

DOI  :  10.1186/s12941-017-0186-0

 received in 2016-10-05, accepted in 2017-03-06,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundAggregatibacter actinomycetemcomitans most commonly causes periodontitis but has been reported to infect heart valves, soft tissue, brain and lungs, and distal bones. Osteomyelitis distal to the jaw is rarely described.Case presentationWe report an unusual and rare case of chronic osteomyelitis caused by A. actinomycetemcomitans in the toe of a paediatric patient, and review the available literature. The infection was managed with intravenous antibiotics followed by oral antibiotics.ConclusionThis is an unusual presentation of A. actinomycetemcomitans causing chronic osteomyelitis presumed due to nidation in a minimally damaged bone, associated with bacteraemia of an oral commensal. It occurred in the toe, without obvious dental predisposition; associated with minimal clinical disturbance and with muted immune response.

【 授权许可】

CC BY   
© The Author(s) 2017