Genome-wide association studies in Plasmodiumspecies

BMC Biology

Commentary

Sunetra Gupta¹  Caroline Buckee¹  Bridget Penman¹  Sean Nee² 

[1] Department of Zoology, University of Oxford, OX1 3PS, Oxford, UK;Institute of Evolutionary Biology, University of Edinburgh, EH9 3JT, Edinburgh, UK;

关键词: Malaria;    Malaria Parasite;    Severe Malaria;    Malaria Endemicity;    Parasite Genome;   

DOI  :  10.1186/1741-7007-8-90

 received in 2010-06-07, accepted in 2010-06-23,  发布年份 2010

来源: Springer

【 摘 要 】

Genome-wide association studies (GWAS) look for correlations between traits of interest and genetic markers spread throughout the genome. A recent study in BMC Genetics has found that populations of the malaria parasite Plasmodium vivax should be amenable to GWAS searching for a genetic basis of parasite pathogenicity. Geographical substructure in populations may, however, prove a problem in interpreting the results.See research article http://www.biomedcentral.com/1471-2156/11/65

【 授权许可】

Unknown   
© Penman et al; licensee BioMed Central Ltd. 2010. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.