Cost-effectiveness analysis of the diarrhea alleviation through zinc and oral rehydration therapy (DAZT) program in rural Gujarat India: an application of the net-benefit regression framework

Cost Effectiveness and Resource Allocation

Research

Sarmila Mazumder¹  Sunita Taneja¹  Christa L. Fischer-Walker²  Robert E. Black²  Amnesty E. LeFevre²  Samuel D. Shillcutt² 

[1] Centre for Health Research and Development, Society for Applied Studies, 45 KaluSarai, 110016, New Delhi, India;Department of International Health, Johns Hopkins Bloomberg School of Public Health, 615 N. Wolfe Street, 21205, Baltimore, MD, USA;

关键词: Diarrhea;    Cost-effectiveness;    Net-benefit regression;    Zinc;    Oral rehydration salts;    India;    Developing countries;    Implementation science;   

DOI  :  10.1186/s12962-017-0070-y

 received in 2016-06-08, accepted in 2017-05-13,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundThis study evaluates the cost-effectiveness of the DAZT program for scaling up treatment of acute child diarrhea in Gujarat India using a net-benefit regression framework.MethodsCosts were calculated from societal and caregivers’ perspectives and effectiveness was assessed in terms of coverage of zinc and both zinc and Oral Rehydration Salt. Regression models were tested in simple linear regression, with a specified set of covariates, and with a specified set of covariates and interaction terms using linear regression with endogenous treatment effects was used as the reference case.ResultsThe DAZT program was cost-effective with over 95% certainty above $5.50 and $7.50 per appropriately treated child in the unadjusted and adjusted models respectively, with specifications including interaction terms being cost-effective with 85–97% certainty.DiscussionFindings from this study should be combined with other evidence when considering decisions to scale up programs such as the DAZT program to promote the use of ORS and zinc to treat child diarrhea.

【 授权许可】

CC BY   
© The Author(s) 2017

【 图 表 】

Fig. 1

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