Epidemiology of urinary tract infections and antibiotics sensitivity among pregnant women at Khartoum North Hospital

Annals of Clinical Microbiology and Antimicrobials

Research

Hamdan Z Hamdan¹  Ishag Adam²  Abdel Haliem M Ziad³  Salah K Ali⁴ 

[1] Faculty of Medicine, Al-Neelain University, Khartoum, Sudan;Faculty of Medicine, University of Khartoum, Khartoum, Sudan;Khartoum North Hospital, Khartoum, Sudan;National health laboratory, Khartoum, Sudan;

关键词: Pregnant Woman;    Urinary Tract Infection;    Amoxicillin;    Norfloxacin;    Bacteriuria;   

DOI  :  10.1186/1476-0711-10-2

 received in 2010-11-14, accepted in 2011-01-18,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundUrinary tract infections (UTI) can lead to poor maternal and perinatal outcomes. Investigating epidemiology of UTI and antibiotics sensitivity among pregnant women is fundamental for care-givers and health planners.MethodsA cross sectional study has been conducted at Khartoum north teaching hospital Antenatal Care Clinic between February-June 2010, to investigate epidemiology of UTI and antibiotics resistance among pregnant women. Structured questionnaires were used to gather data from pregnant women. UTI was diagnosed using mid stream urine culture on standard culture mediaResultsOut of 235 pregnant women included, 66 (28.0%) were symptomatic and 169 (71.9%) asymptomatic. the prevalence of bacteriuria among symptomatic and asymptomatic pregnant women were (12.1%), and (14.7%) respectively, with no significant difference between the two groups (P = 0.596), and the overall prevalence of UTI was (14.0%). In multivariate analyses, age, gestational age, parity, and history of UTI in index pregnancy were not associated with bacteriuria. Escherichia coli (42.4%) and S. aureus (39.3%) were the commonest isolated bacteria. Four, 2, 2, 3, 4, 2 and 0 out of 14 E. coli isolates, showed resistance to amoxicillin, naladixic acid, nitrofurantoin, ciprofloxacin, co-trimoxazole, amoxicillin/clavulanate and norfloxacin, respectivelyConclusionEscherichia coli were the most prevalent causative organisms and showing multi drug resistance pattern, asymptomatic bacteriuria is more prevalent than symptomatic among pregnant women. Urine culture for screening and diagnosis purpose for all pregnant is recommended.

【 授权许可】

Unknown   
© Hamdan et al; licensee BioMed Central Ltd. 2011. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.