Efficacy of transanal tube placement after anterior resection for rectal cancer: a systematic review and meta-analysis

World Journal of Surgical Oncology

Research

Shuanhu Wang¹  Mulin Liu¹  Congqiao Jiang¹  Shiqing Li¹  Zongbing Zhang¹ 

[1] Department of Gastrointestinal surgery, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui Province, China;

关键词: Rectal cancer;    Transanal tube;    Anastomotic leakage;   

DOI  :  10.1186/s12957-016-0854-0

 received in 2015-07-13, accepted in 2016-03-24,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundAnastomotic leakage is a serious complication that can occur after anterior resection of the rectum. There is a question regarding whether the placement of a transanal tube can decrease the rate of anastomotic leakage. The aim of this systematic review and meta-analysis was to evaluate the efficacy of transanal tube placement after anterior resection.MethodsWe searched three major databases (PubMed, Embase, and the Cochrane Library) up until January 2015 for studies evaluating the benefit of transanal tubes after anterior resection for rectal cancer. The primary outcome measure was the rate of clinical anastomotic leakage. Secondary outcome was the rate of reoperation. Pooled risk ratios (RR) with 95 % confidence intervals (CI) were obtained using random effects models.ResultsOne randomized controlled trial and three observational studies involving 909 patients met inclusion criteria. Clinical anastomotic leakage occurred in 3.49 % (14 of 401) of patients with transanal tubes and 12.01 % (61 of 508) of patients without transanal tubes. Meta-analysis of the studies showed a lower risk of anastomotic leakage (RR, 0.32; 95 % CI 0.18–0.58) and reoperation related to leakage (RR, 0.19; 95 % CI 0.08–0.46) when the transanal tube was placed.ConclusionsWhile studies are few and mostly observational, the data to date indicate that placement of a transanal tube decreases the rate of clinical anastomotic leakage and reoperation related to leakage. More studies are needed to confirm these findings.

【 授权许可】

CC BY   
© Wang et al. 2016