Metabolic response to three different diets in lean cats and cats predisposed to overweight

BMC Veterinary Research

Research Article

Diana Frey¹  Claudia Keller²  Brigitta Wichert²  Annette Liesegang² 

[1] Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland;Institute of Animal Nutrition, University of Zurich, Winterthurerstr, 270, CH-8057, Zurich, Switzerland;

关键词: Glucose;    Insulin;    Protein;    Fat;    Carbohydrate;   

DOI  :  10.1186/s12917-017-1107-3

 received in 2015-12-16, accepted in 2017-06-12,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundThe existence of a genetic predisposition to obesity is commonly recognized in humans and rodents. Recently, a link between genetics and overweight was shown in cats. The goal of this study was to identify the effect of diet composition on plasma levels of glucose, insulin, free fatty acids and triglycerides in cats receiving different diets (high-carbohydrate, high-fat and high-protein diets).ResultsInsulin and leptin concentrations were significantly correlated with phenotype. Insulin levels were lower, whereas leptin levels were higher in cats predisposed to overweight. The other blood parameters were not correlated with phenotype. Intake of the high-carbohydrate diet resulted in higher insulin concentrations compared with the two other diets. Insulin levels were within the values described for non-obese cats in previous studies.ConclusionsThere was no difference in metabolic response between the two groups. As the high-carbohydrate diet led to the highest insulin blood concentrations, it might be useful to avoid such diets in cats predisposed to overweight. In addition, even cats with genetically linked obesity can regain insulin sensitivity after weight loss.

【 授权许可】

CC BY   
© The Author(s). 2017