Diabetes mellitus type 2 and other chronic non-communicable diseases in the central region, Saudi Arabia (riyadh cohort 2): a decade of an epidemic

BMC Medicine

Research Article

Shaun Louie Sabico¹  Majed S Alokail²  Nasser M Al-Daghri²  Omar S Al-Attas²  Khalid M Alkharfy³  George P Chrousos⁴  Mansour Yousef⁵ 

[1] Biomarkers Research Program, Biochemistry Department, College of Science, King Saud University, 11451, Riyadh, Saudi Arabia;Biomarkers Research Program, Biochemistry Department, College of Science, King Saud University, 11451, Riyadh, Saudi Arabia;Center of Excellence in Biotechnology Research, King Saud University, 11451, Riyadh, Saudi Arabia;Biomarkers Research Program, Biochemistry Department, College of Science, King Saud University, 11451, Riyadh, Saudi Arabia;Center of Excellence in Biotechnology Research, King Saud University, 11451, Riyadh, Saudi Arabia;Clinical Pharmacy Department, College of Pharmacy, King Saud University, 11451, Riyadh, Saudi Arabia;Biomarkers Research Program, Biochemistry Department, College of Science, King Saud University, 11451, Riyadh, Saudi Arabia;Division of Endocrinology, Metabolism & Diabetes, University of Athens Medical School, Children's Hospital Aghia Sophia,, 115 27, Athens, Greece;Health Affairs for Riyadh Region, Ministry of Health, 11176, Riyadh, Saudi Arabia;

关键词: Gestational Diabetes Mellitus;    Impaired Fasting Glucose;    Fasting Plasma Glucose Level;    Crude Prevalence;    Saudi Population;   

DOI  :  10.1186/1741-7015-9-76

 received in 2011-03-09, accepted in 2011-06-20,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundFollow-up epidemiologic studies are needed to assess trends and patterns of disease spread. No follow-up epidemiologic study has been done in the Kingdom of Saudi Arabia to assess the current prevalence of major chronic, noncommunicable diseases, specifically in the urban region, where modifiable risk factors remain rampant. This study aims to fill this gap.MethodsA total of 9,149 adult Saudis ages seven to eighty years (5,357 males (58.6%) and 3,792 females (41.4%)) were randomly selected from the Riyadh Cohort Study for inclusion. Diagnosis of type 2 diabetes mellitus (DMT2) and obesity were based on the World Health Organization definitions. Diagnoses of hypertension and coronary artery disease (CAD) were based on the Seventh Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure and American Heart Association criteria, respectively.ResultsThe overall crude prevalence of DMT2 was 23.1% (95% confidence interval (95% CI) 20.47 to 22.15). The age-adjusted prevalence of DMT2 was 31.6%. DMT2 prevalence was significantly higher in males, with an overall age-adjusted prevalence of 34.7% (95% CI 32.6 to 35.4), than in females, who had an overall age-adjusted prevalence of 28.6% (95% CI 26.7 to 29.3) (P < 0.001). The overall crude prevalence of obesity was 31.1% (95% CI 30.1 to 32.0). The age-adjusted prevalence of obesity was 40.0%. The prevalence of obesity was higher in females, with an overall prevalence of 36.5% (95% CI 35.1 to 37.83), than in males (25.1% (95% CI 23.7 to 26.3)) (P < 0.001). The age-adjusted prevalence of hypertension and CAD were 32.6% (95% CI 31.7 to 33.6) and 6.9% (95% CI 6.4 to 7.4), respectively.ConclusionComparisons of our findings with earlier data show that the prevalence of DMT2, hypertension and CAD in Riyadh, Saudi Arabia, has alarmingly worsened. Aggressive promotion of public awareness, continued screening and early intervention are pivotal to boosting a positive response.

【 授权许可】

CC BY   
© Al-Daghri et al; licensee BioMed Central Ltd. 2011