期刊论文详细信息
Reproductive Biology and Endocrinology
First-trimester diagnosis and management of Cesarean scar pregnancies after in vitro fertilization-embryo transfer: a retrospective clinical analysis of 12 cases
Research
Yan Yi1  Yan Ouyang2  Ge Lin2  Guangxiu Lu2  Fei Gong2  Xihong Li3 
[1] Institute of Reproductive and stem cell Engineering, Central South University, Xiangya Road, 410008, Changsha, Hunan, P.R. China;Institute of Reproductive and stem cell Engineering, Central South University, Xiangya Road, 410008, Changsha, Hunan, P.R. China;Reproductive and Genetic Hospital of Citic-Xiangya, Xiangya Road, 410078, Changsha, Hunan, P.R. China;Reproductive and Genetic Hospital of Citic-Xiangya, Xiangya Road, 410078, Changsha, Hunan, P.R. China;
关键词: Cesarean scar pregnancy;    Heterotopic cesarean scar pregnancy;    First-trimester;    Transvaginal sonography;    Diagnosis;    Management;    In vitro fertilization-embryo transfer;   
DOI  :  10.1186/s12958-015-0120-2
 received in 2015-08-18, accepted in 2015-11-02,  发布年份 2015
来源: Springer
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【 摘 要 】

BackgroundAlthough Caesarean scar pregnancy (CSP) is rare, it can cause life-threatening complications. The increasing rate of Cesarean delivery plus rapid development of in vitro fertilization-embryo transfer (IVF-ET) may increase the occurrence of CSP as well as the ratio of heterotopic CSP (HCSP)/CSP. Therefore, early diagnosis and management of CSP are necessary to avoid serious complications. And the purpose of this article is to evaluate the importance and feasibility of the first-trimester diagnosis and management of CSP after IVF-ET.MethodsAll the 12 cases were secondary infertility patients who had a history of Cesarean section and underwent IVF-ET in our reproductive center. All cases with CSP were diagnosed using transvaginal color Doppler sonography (TVS). Medical, surgical and expectant managements were implemented, and the management results were traced.ResultsPatients with CSP (n = 12) were diagnosed from January 2011 to April 2015, 6 (50 %) of which were HCSP. The prevalence of CSP was 1:1688 pregnancies. The gestational age ranged from 5 + 3 to 7 + 4 weeks in all CSP, and from 5 + 6 to 7 + 4 weeks in HCSP at diagnosis. Five patients received successful surgical treatment. The success rate of medical and expectant management was 50 % (1/2) and 100 % (5/5), respectively. One patient with failed medical management needed an emergency laparotomy to evacuate CSP. The uterus was preserved in all 12 patients.ConclusionsThe Caesarean section and IVF-ET may increase the ratio of HCSP/CSP. TVS is a noninvasive and effective tool for use in diagnosing CSP. CSP should be carefully excluded in patients who have had a history of Caesarean section. Early diagnosis of CSP in the first trimester may contribute towards the preservation of uterus as well as intrauterine pregnancy (IUP) in HCSP.

【 授权许可】

CC BY   
© Ouyang et al. 2015

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