Relatively speaking

BMC Biology

Comment

Graham Bell¹ 

[1] BMC Biology, BioMed Central, 236 Gray’s Inn Road, WC1X 8HB, London, UK;

关键词: Cell Death;    Untreated Control;    Signalling Molecule;    Untreated Cell;    Treated Cell;   

DOI  :  10.1186/s12915-016-0265-2

来源: Springer

【 摘 要 】

Protein X is a signalling molecule that stimulates apoptosis. Treatment of cells with Protein X results in five times higher levels of cell death than those seen in untreated cells (wild type), as measured by Caspase-positive cells. Based on previous work, the authors identify Protein Y as the putative receptor for Protein X and here try to test whether this is indeed the case. They claim that in a geneY mutant, where no receptor is expressed, treatment with Protein X no longer results in increased cell death, supporting the hypothesis that Protein Y is the receptor for signalling molecule X.

【 授权许可】

CC BY   
© Bell. 2016