Malaria-like symptoms associated with a natural Plasmodium reichenowi infection in a chimpanzee

Malaria Journal

Case Report

Barthélémy Ngoubangoye¹  Anaïs Herbert¹  Patrick Durand²  François Renaud²  Céline Arnathau²  Cheikh Tidiane Ba³  Anne Meyer⁴  Eric Willaume⁴  Alain Prince Okouga⁵  Benjamin Ollomo⁵  Diamella Nancy Moukodoum⁵  Julie Magnus⁵  Virginie Rougeron⁶  Franck Prugnolle⁶  Larson Boundenga⁷ 

[1] Centre de Primatologie, Centre International de Recherches Médicales de Franceville, BP 769, Franceville, Gabon;Laboratoire MIVEGEC; UM1-CNRS 5290-IRD 224, IRD Montpellier, Montpellier, France;Laboratoire d’Écologie et Biologie évolutive, Département de Biologie Animale, Faculté des Sciences et Techniques, Université Cheikh Anta Diop de Dakar, BP 5005, Dakar, Senegal;Société d’Exploitation du Parc de la Lékédi, Bakoumba, Gabon;Unité de Biodiversité, Ecologie et Evolution des Parasites (UBEEP), Centre International de Recherches Médicales de Franceville, BP 769, Franceville, Gabon;Unité de Biodiversité, Ecologie et Evolution des Parasites (UBEEP), Centre International de Recherches Médicales de Franceville, BP 769, Franceville, Gabon;Laboratoire MIVEGEC; UM1-CNRS 5290-IRD 224, IRD Montpellier, Montpellier, France;Unité de Biodiversité, Ecologie et Evolution des Parasites (UBEEP), Centre International de Recherches Médicales de Franceville, BP 769, Franceville, Gabon;Laboratoire d’Écologie et Biologie évolutive, Département de Biologie Animale, Faculté des Sciences et Techniques, Université Cheikh Anta Diop de Dakar, BP 5005, Dakar, Senegal;

关键词: Plasmodium;    Pan troglodytes;    Chimpanzee;    Symptom;    Malaria;    Anaemia;    Hyperthermia;    Fever;   

DOI  :  10.1186/s12936-015-0743-y

 received in 2015-02-18, accepted in 2015-05-20,  发布年份 2015

来源: Springer

【 摘 要 】

Although Plasmodium infections have never been clearly associated with symptoms in non-human primates, the question of the pathogenicity of Plasmodium parasites in non-human primates still remains unanswered. A young chimpanzee, followed before and after release to a sanctuary, in a semi-free ranging enclosure located in an equatorial forest, showed fever and strong anaemia associated with a high Plasmodium reichenowi infection, shortly after release. The animal recovered from anaemia after several months despite recurrent infection with other Plasmodium species. This may be the first description of malaria-like symptoms in a chimpanzee infected with Plasmodium.

【 授权许可】

CC BY   
© Herbert et al. 2015