Postprandial lipid responses to an alpha-linolenic acid-rich oil, olive oil and butter in women: A randomized crossover trial

Lipids in Health and Disease

Research

Julia Svensson¹  Anna Rosenquist²  Lena Ohlsson² 

[1] Department of Biotechnology, Lund University, P.O. Box 124, SE-221 00, Lund, Sweden;Department of Clinical Sciences, Laboratory of Gastroenterology and Nutrition, Biomedical Centre B11, Lund University, SE-221 84, Lund, Sweden;Department of Clinical Sciences, Laboratory of Gastroenterology and Nutrition, Biomedical Centre B11, Lund University, SE-221 84, Lund, Sweden;

关键词: Oleic Acid;    Test Meal;    Postprandial Lipaemia;    Postprandial Effect;    Plasma Lipid Fraction;   

DOI  :  10.1186/1476-511X-10-106

 received in 2011-05-13, accepted in 2011-06-28,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundPostprandial lipaemia varies with gender and the composition of dietary fat due to the partitioning of fatty acids between beta-oxidation and incorporation into triacylglycerols (TAGs). Increasing evidence highlights the importance of postprandial measurements to evaluate atherogenic risk. Postprandial effects of alpha-linolenic acid (ALA) in women are poorly characterized. We therefore studied the postprandial lipid response of women to an ALA-rich oil in comparison with olive oil and butter, and characterized the fatty acid composition of total lipids, TAGs, and non-esterified fatty acids (NEFAs) in plasma.MethodsA randomized crossover design (n = 19) was used to compare the postprandial effects of 3 meals containing 35 g fat. Blood samples were collected at regular intervals for 7 h. Statistical analysis was carried out with ANOVA (significant difference = P < 0.05).ResultsNo significant difference was seen in incremental area under the curve (iAUC) plasma-TAG between the meals. ALA and oleic acid levels were significantly increased in plasma after ALA-rich oil and olive oil meals, respectively. Palmitic acid was significantly increased in plasma-TAG after the butter meal. The ratios of 18:2 n-6 to18:3 n-3 in plasma-TAGs, three and seven hours after the ALA-rich oil meal, were 1.5 and 2.4, respectively. The corresponding values after the olive oil meal were: 13.8 and 16.9; and after the butter meal: 9.0 and 11.6.ConclusionsThe postprandial p-TAG and NEFA response in healthy pre-menopausal women was not significantly different after the intake of an ALA-rich oil, olive oil and butter. The ALA-rich oil significantly affected different plasma lipid fractions and improved the ratio of n-6 to n-3 fatty acids several hours postprandially.

【 授权许可】

Unknown   
© Svensson et al; licensee BioMed Central Ltd. 2011. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.