Prevalence of clinically captured and confirmed malaria among HIV seropositve clinic attendants in five hospitals in Ghana

Malaria Journal

Research

Emmanuel Mahama¹  Kwaku Poku Asante¹  Sam Newton¹  Dennis Adu-Gyasi¹  George Adjei¹  Frank Baiden²  Alexander Manu²  Seth Owusu-Agyei²  John DH Porter³  Caterina I Fanello⁴  Dan Korbel⁵ 

[1] Kintampo Health Research Centre, P. O. Box 200, Kintampo North, Ghana;Kintampo Health Research Centre, P. O. Box 200, Kintampo North, Ghana;London School of Hygiene and Tropical Medicine, Keppel Street, WC1E 7HT, London, UK;London School of Hygiene and Tropical Medicine, Keppel Street, WC1E 7HT, London, UK;Mahidol-Oxford Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand;London School of Hygiene and Tropical Medicine, Keppel Street, WC1E 7HT, London, UK;The Wellcome Trust Gibbs Building, 215 Euston Road, NW1 2BE, London, UK;

关键词: Malaria;    Rapid Diagnostic Test;    Clinical Malaria;    National Health Insurance Scheme;    Case Record Form;   

DOI  :  10.1186/1475-2875-12-382

 received in 2013-06-18, accepted in 2013-10-28,  发布年份 2013

来源: Springer

【 摘 要 】

BackgroundMalaria is associated with an increase in HIV viral load and a fall in CD4-cell count. Conversely, HIV infection disrupts the acquired immune responses to malaria and the efficacy of antimalarial drugs. This study was carried out in five Ghanaian hospitals to estimate the prevalence of clinically confirmed malaria among HIV patients by evaluating their hospital records.MethodsThis retrospective descriptive cross sectional study reviewed and collected data on malaria, using Case Record Forms from HIV patients’ folders in five hospitals in Ghana.ResultsThere were 933 patients records made up of 272 (29.2%) males and 661 (70.8%) females. Majority of the patients were aged between 21–40 (63.6%) years and the rest were between the ages 1–20 (2.8%) years, 41–60 (31.6%) years and 61–80 (2.1%) years of age.A total of 38.1% (355/933) of the patients were clinically suspected of having clinical malaria. Of these 339 (95.5%) were referred to the laboratory for confirmation of the diagnosis of malaria. Only 4.4% (15/339) of patients tested were confirmed as cases of malaria among the patients that were clinically suspected of having malaria and subsequently confirmed. Fever, was not significantly associated with a confirmed diagnosis of malaria [OR = 3.11, 95% CI: (0.63, 15.37), P = 0.142].ConclusionsThere was a 4.4% prevalence of confirmed malaria and 38.1% of presumptively diagnosed malaria from the case records of HIV patients from the selected hospitals in Ghana.

【 授权许可】

CC BY   
© Adu-Gyasi et al.; licensee BioMed Central Ltd. 2013