Major surgery in an osteosarcoma patient refusing blood transfusion: case report

World Journal of Surgical Oncology

Case Report

Raja Rajendram¹  Rukmanikanthan Shanmugam²  Vivek A Singh²  Amreeta Dhanoa³ 

[1] Department of Anaesthesia, University Malaya Medical Center, Malaysia;Department of Orthopaedic Surgery, University Malaya Medical Center, Malaysia;Jeffrey Cheah School of Medicine and Health Sciences, Monash University Sunway Campus, Malaysia;

关键词: Osteosarcoma;    Proximal Tibia;    Recombinant Human Erythropoietin;    Minimize Blood Loss;    Recombinant Erythropoietin;   

DOI  :  10.1186/1477-7819-8-96

 received in 2010-07-06, accepted in 2010-11-08,  发布年份 2010

来源: Springer

【 摘 要 】

We describe an unusual case of osteosarcoma in a Jehovah's Witness patient who underwent chemotherapy and major surgery without the need for blood transfusion. This 16-year-old girl presented with osteosarcoma of the right proximal tibia requiring proximal tibia resection, followed by endoprosthesis replacement. She was successfully treated with neoadjuvant chemotherapy and surgery with the support of haematinics, granulocyte colony-stimulating factor, recombinant erythropoietin and intraoperative normovolaemic haemodilution. This case illustrates the importance of maintaining effective, open communication and exploring acceptable therapeutic alternative in the management of these patients, whilst still respecting their beliefs.

【 授权许可】

CC BY   
© Dhanoa et al; licensee BioMed Central Ltd. 2010