Summit on cell therapy for cancer: The importance of the interaction of multiple disciplines to advance clinical therapy

Journal of Translational Medicine

Review

Cornelis JM Melief¹  David F Stroncek²  John J O'Shea³ 

[1] Department of Immunohematology and Blood Transfusion Leiden University Medical Center, 2300, Leiden, RC, the Netherlands;Department of Transfusion Medicine Clinical Center, NIH 10 Center Drive-MSC-1288 Building 10, Room 3C720, 20892, Bethesda, Maryland, USA;Molecular Immunology and Inflammation Branch National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Building 10, Room 6N204, 20892, Bethesda, Maryland, USA;

关键词: Natural Killer Cell;    Hematopoietic Stem Cell Transplantation;    Tumor Infiltrate Lymphocyte;    Cellular Therapy;    Stem Cell Biology;   

DOI  :  10.1186/1479-5876-9-107

 received in 2011-06-22, accepted in 2011-07-08,  发布年份 2011

来源: Springer

【 摘 要 】

The field of cellular therapy of cancer is moving quickly and the issues involved with its advancement are complex and wide ranging. The growing clinical applications and success of adoptive cellular therapy of cancer has been due to the rapid evolution of immunology, cancer biology, gene therapy and stem cell biology and the translation of advances in these fields from the research laboratory to the clinic. The continued development of this field is dependent on the exchange of ideas across these diverse disciplines, the testing of new ideas in the research laboratory and in animal models, the development of new cellular therapies and GMP methods to produce these therapies, and the testing of new adoptive cell therapies in clinical trials. The Summit on Cell Therapy for Cancer to held on November 1 and 2, 2011 at the National Institutes of Health (NIH) campus will include a mix of perspectives, concepts and ideas related to adoptive cellular therapy that are not normally presented together at any single meeting. This novel assembly will generate new ideas and new collaborations and possibly increase the rate of advancement of this field.

【 授权许可】

Unknown   
© Melief et al; licensee BioMed Central Ltd. 2011. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.