Prolonged outbreak of Serratia marcescens in Tartu University Hospital: a case–control study

BMC Infectious Diseases

Research Article

Kaidi Telling¹  Piret Mitt¹  Vivika Adamson¹  Matti Maimets²  Paul Naaber³  Heti Pisarev⁴  Tuuli Metsvaht⁵ 

[1] Department of Infection Control, Tartu University Hospital, 50406, Puusepa 1a, Tartu, Estonia;Department of Infection Control, Tartu University Hospital, 50406, Puusepa 1a, Tartu, Estonia;Department of Internal Medicine, Tartu University Hospital, Tartu, Estonia;Department of Medical Microbiology, Stavanger University Hospital, Stavanger, Norway;Department of Public Health, University of Tartu, Tartu, Estonia;Pediatric Intensive Care Unit, Intensive Care Clinic, Tartu University Hospital, Tartu, Estonia;

关键词: Health Care Worker;    Neonatal Intensive Care Unit;    Pediatric Intensive Care Unit;    Hand Hygiene;    Serratia Marcescens;   

DOI  :  10.1186/1471-2334-12-281

 received in 2011-09-22, accepted in 2012-10-23,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundThe aim of our study was to investigate and control an outbreak and identify risk factors for colonization and infection with Serratia marcescens in two departments in Tartu University Hospital.MethodsThe retrospective case–control study was conducted from July 2005 to December 2006. Molecular typing by pulsed field gel electrophoresis was used to confirm the relatedness of Serratia marcescens strains. Samples from the environment and from the hands of personnel were cultured.ResultsThe outbreak involved 210 patients, 61 (29%) developed an infection, among them 16 were invasive infections. Multivariate analysis identified gestational age, arterial catheter use and antibiotic treatment as independent risk factors for colonization and infection with Serratia marcescens. Molecular typing was performed on 83 Serratia marcescens strains, 81 of them were identical and 2 strains were different.ConclusionsGiven the occasionally severe consequences of Serratia marcescens in infants, early implementation of aggressive infection control measures involving patients and mothers as well as the personnel is of utmost importance.

【 授权许可】

CC BY   
© Adamson et al.; licensee BioMed Central Ltd. 2012