Urinary bisphenol A concentrations in girls from rural and urban Egypt: a pilot study

Environmental Health

Research

Dana C Dolinoy¹  Muna S Nahar¹  Kristen Battige¹  Justin A Colacino²  Laura S Rozek³  Amr S Soliman⁴  Antonia M Calafat⁵  Ibrahim A Seifeldin⁶  Ahmed Hablas⁶ 

[1] Department of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor, MI, USA;Department of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor, MI, USA;Center for Global Health, University of Michigan, Ann Arbor, MI, USA;Department of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor, MI, USA;Center for Global Health, University of Michigan, Ann Arbor, MI, USA;Department of Otolaryngology, University of Michigan, Ann Arbor, MI, USA;Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA;Center for Global Health, University of Michigan, Ann Arbor, MI, USA;National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, USA;Tanta Cancer Center and the Gharbiah Cancer Society, Tanta, Egypt;

关键词: Egypt;    Urban;    Rural;    Bisphenol A;   

DOI  :  10.1186/1476-069X-11-20

 received in 2011-12-15, accepted in 2012-04-02,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundExposure to endocrine active compounds, including bisphenol A (BPA), remains poorly characterized in developing countries despite the fact that behavioral practices related to westernization have the potential to influence exposure. BPA is a high production volume chemical that has been associated with metabolic dysfunction as well as behavioral and developmental effects in people, including children. In this pilot study, we evaluate BPA exposure and assess likely pathways of exposure among girls from urban and rural Egypt.MethodsWe measured urinary concentrations of total (free plus conjugated) species of BPA in spot samples in urban (N = 30) and rural (N = 30) Egyptian girls, and compared these concentrations to preexisting data from age-matched American girls (N = 47) from the U.S. National Health and Nutrition Examination Survey (NHANES). We also collected anthropometric and questionnaire data regarding food storage behaviors to assess potential routes of exposure.ResultsUrban and rural Egyptian girls exhibited similar concentrations of urinary total BPA, with median unadjusted values of 1.00 and 0.60 ng/mL, respectively. Concentrations of urinary BPA in this group of Egyptian girls (median unadjusted: 0.70 ng/mL) were significantly lower compared to age-matched American girls (median unadjusted: 2.60 ng/mL) according to NHANES 2009-2010 data. Reported storage of food in plastic containers was a significant predictor of increasing concentrations of urinary BPA.ConclusionsDespite the relatively low urinary BPA concentrations within this Egyptian cohort, the significant association between food storage behaviors and increasing urinary BPA concentration highlights the need to understand food and consumer product patterns that may be closing the gap between urban and rural lifestyles.

【 授权许可】

Unknown   
© Nahar et al; licensee BioMed Central Ltd. 2012. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.