期刊论文

【摘要】

The ability to identify key biomolecules and molecular changes associated with cancer malignancy and the capacity to monitor the therapeutic outcome against these targets is critically important for cancer treatment. Recent developments in molecular imaging based on magnetic resonance (MR) techniques have provided researchers and clinicians with new tools to improve most facets of cancer care. Molecular imaging is broadly described as imaging techniques used to detect molecular signature at the cellular and gene expression levels. This article reviews both established and emerging molecular MR techniques in oncology and discusses the potential of these techniques in improving the clinical cancer care. It also discusses how molecular MR, in conjunction with other structural and functional MR imaging techniques, paves the way for developing tailored treatment strategies to enhance cancer care.

【授权许可】

CC BY
© Haris et al. 2015

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Journal of Translational Medicine
Molecular magnetic resonance imaging in cancer
Review
Arshi Rizwan¹ Anup Singh² Ravinder Reddy³ Hari Hariharan³ Ena Wang⁴ Francesco M. Marincola⁴ Mohammad Haris⁴ Santosh K. Yadav⁴
[1] All India Institute of Medical Sciences, New Delhi, India;Center for Biomedical Engineering, Indian Institute of Technology, Delhi, India;Center for Magnetic Resonance and Optical Imaging, Department of Radiology, University of Pennsylvania, 19104, Philadlephia, PA, USA;Sidra Medical and Research Center, 26999, Doha, Qatar;
关键词: Cancer; Magnetic resonance imaging; Magnetic resonance spectroscopy; Hyperpolarization; Chemical exchange saturation transfer (CEST) imaging; Reporter genes; Cancer immunotherapy;
DOI : 10.1186/s12967-015-0659-x
received in 2015-08-05, accepted in 2015-09-03, 发布年份 2015
来源: Springer
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