Value of black blood T2* cardiovascular magnetic resonance

Journal of Cardiovascular Magnetic Resonance

Technical Notes

Gillian C Smith¹  John Paul Carpenter¹  David N Firmin¹  Dudley J Pennell¹  Mohammed H Alam¹  Taigang He¹ 

[1] CMR Unit, Royal Brompton Hospital, Sydney Street, SW3 6NP, London, UK;National Heart & Lung Institute, Imperial College London, Guy Scadding Building, Dovehouse Street, SW3 6LY, London, UK;

关键词: Cardiovascular Magnetic Resonance;    Iron Overload;    Siderosis;    Black Blood;    Double Inversion Recovery;   

DOI  :  10.1186/1532-429X-13-21

 received in 2010-12-17, accepted in 2011-03-14,  发布年份 2011

来源: Springer

【 摘 要 】

PurposeTo assess whether black blood T2* cardiovascular magnetic resonance is superior to conventional white blood imaging of cardiac iron in patients with thalassaemia major (TM).Materials and methodsWe performed both conventional white blood and black blood T2* CMR sequences in 100 TM patients to determine intra and inter-observer variability and presence of artefacts. In 23 patients, 2 separate studies of both techniques were performed to assess interstudy reproducibility.ResultsCardiac T2* values ranged from 4.5 to 43.8 ms. The mean T2* values were not different between black blood and white blood acquisitions (20.5 vs 21.6 ms, p = 0.26). Compared with the conventional white blood diastolic acquisition, the coefficient of variance of the black blood CMR technique was superior for intra-observer reproducibility (1.47% vs 4.23%, p < 0.001), inter-observer reproducibility (2.54% vs 4.50%, p < 0.001) and inter-study reproducibility (4.07% vs 8.42%, p = 0.001). Assessment of artefacts showed a superior score for black blood vs white blood scans (4.57 vs 4.25; p < 0.001).ConclusionsBlack blood T2* CMR has superior reproducibility and reduced imaging artefacts for the assessment of cardiac iron, in comparison with the conventional white blood technique, which make it the preferred technique for clinical practice.

【 授权许可】

Unknown   
© Smith et al; licensee BioMed Central Ltd. 2011. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.