Impact of self-reported physical activity and health promotion behaviors on lung cancer survivorship

Health and Quality of Life Outcomes

Research

Jeff A. Sloan¹  Jason A. Wampfler¹  Ping Yang¹  Heshan Liu¹  Paul J. Novotny¹  Andrea L. Cheville²  Matthew M. Clark³  Yolanda I. Garces⁴ 

[1] Department of Health Sciences Research, 200 First St SW, 55905, Rochester, MN, USA;Department of Physical Medicine and Rehabilitation, Rochester, USA;Department of Psychiatry and Psychology, Mayo Clinic, 55905, Rochester, MN, USA;Department of Radiation Oncology, Rochester, USA;

关键词: Physical Activity;    Physical Activity Level;    Aerobic Fitness;    Health Promotion Behavior;    North Central Cancer Treatment Group;   

DOI  :  10.1186/s12955-016-0461-3

 received in 2015-08-28, accepted in 2016-03-31,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundThere is some initial evidence that an enhanced physical activity level can improve fquality of life, and possibly survival among patients with lung cancer. The primary aim of this project was to evaluate the impact of physical activity on the quality and quantity of life of lung cancer survivors.MethodsBetween January 1, 1997, and December 31, 2009, a total of 1466 lung cancer survivors completed a questionnaire with patient-reported outcomes for quality of life (QOL), demographics, disease and clinical characteristics, and a measure of physical activity (Baecke Questionnaire). Chi-square tests compared lung cancer survivors who reported being physically active versus not on a variety of the other covariates. Kaplan-Meier estimates and Cox models evaluated the prognostic importance of physical activity level on Overall Survival (OS).ResultsRoughly half of the lung cancer survivors had advanced stage disease at the time of survey. Treatment prevalence rates were 61, 54, and 33 % for surgery, chemotherapy and radiotherapy, respectively. The majority (77 %) of survivors reported themselves as physically active. Physically active survivors reported greater activity across all individual Baecke items. Lung cancer survivor-reported QOL indicated the benefits of physical activity in all domains. Survivors receiving chemotherapy or radiation at the time of questionnaire completion were less likely to be physically active (74 and 73 % respectively). In contrast, 84 % of surgical patients were physically active. Disease recurrence rates were the same for physically active and inactive patients (81 % vs 82 %, p = 0.62). Physically active patients survived an average of 4 more years than those who were not physically active (8.4 years versus 4.4 years respectively, log rank p < 0.0001).ConclusionsBeing physically active was related to profound advantages in QOL and survival in a large sample of lung cancer survivors.

【 授权许可】

CC BY   
© Sloan et al. 2016