Biomedical research in a Digital Health Framework

Journal of Translational Medicine

Research

Dieter Maier¹  Diego Herrera²  Magí Lluch-Ariet³  Felip Miralles³  Isaac Cano⁴  Susana Kalko⁴  Josep Roca⁵  Marta Cascante⁶  David Gomez-Cabrero⁷  Jesper Tegnér⁷ 

[1] Biomax Informatics AG, Robert-Koch-Str. 2, Planegg, Germany;Departament de Bioquimica i Biologia Molecular i IBUB, Facultat de Biologia, Universitat de Barcelona, 08028, Barcelona, Spain;Almirall R&D, 08980 Sant Feliu de Llobregat, Barcelona, Spain;Department of eHealth, Barcelona Digital, Roc Boronat 117, 08017, Barcelona, Catalunya, Spain;IDIBAPS-Hospital Clínic, CIBERES, Universitat de Barcelona, 08036, Barcelona, Catalunya, Spain;IDIBAPS-Hospital Clínic, CIBERES, Universitat de Barcelona, 08036, Barcelona, Catalunya, Spain;Centro de Investigacíon Biomédica en Red de Enfermedades Respiratorias (CIBERES), Bunyola, Balearic Islands;IDIBAPS-Hospital Clínic, CIBERES, Universitat de Barcelona, 08036, Barcelona, Catalunya, Spain;Departament de Bioquimica i Biologia Molecular i IBUB, Facultat de Biologia, Universitat de Barcelona, 08028, Barcelona, Spain;Unit of Computational Medicine, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden;

关键词: Biomedical Research;    Chronic care;    Clinical Decision Support Systems;    Integrated Health Care Systems;    Patient Decision Support Systems;    Personal Health Folder;   

DOI  :  10.1186/1479-5876-12-S2-S10

来源: Springer

【 摘 要 】

This article describes a Digital Health Framework (DHF), benefitting from the lessons learnt during the three-year life span of the FP7 Synergy-COPD project. The DHF aims to embrace the emerging requirements - data and tools - of applying systems medicine into healthcare with a three-tier strategy articulating formal healthcare, informal care and biomedical research. Accordingly, it has been constructed based on three key building blocks, namely, novel integrated care services with the support of information and communication technologies, a personal health folder (PHF) and a biomedical research environment (DHF-research). Details on the functional requirements and necessary components of the DHF-research are extensively presented. Finally, the specifics of the building blocks strategy for deployment of the DHF, as well as the steps toward adoption are analyzed. The proposed architectural solutions and implementation steps constitute a pivotal strategy to foster and enable 4P medicine (Predictive, Preventive, Personalized and Participatory) in practice and should provide a head start to any community and institution currently considering to implement a biomedical research platform.

【 授权许可】

CC BY   
© Cano et al.; licensee BioMed Central Ltd. 2014