Health-related quality of life in pregnant women living with HIV: a comparison of EQ-5D and SF-12

Health and Quality of Life Outcomes

Research

Jun Yu¹  Ting Tan¹  Lin Lu²  Xiaowen Wang³  Hongzhuan Luo⁴  Yuyan Yang⁵  Zhanqin Li⁶  Liyuan Yang⁷  Xiumin Liang⁸  Jiarui Zheng⁹  Guangping Guo⁹  Ling Zhou⁹ 

[1] Department of Public Health, Kunming Medical University, Yunnan, China;Department of Public Health, Kunming Medical University, Yunnan, China;Health and Family Planning Commission of Yunnan Province, No. 309, Guomao Street, Kunming, Yunnan Province, China;Department of Public Health, Kunming Medical University, Yunnan, China;Yunnan Centers for Disease Control and Prevention, Yunnan, China;Fengqing County Centers for Disease Control and Prevention, Yunnan, China;Longchuan County Maternal and Child Health Care hospital, Yunnan, China;Longling County Centers for Disease Control and Prevention, Yunnan, China;Longling County Maternal and Child Health Care hospital, Yunnan, China;Yiliang County Centers for Disease Control and Prevention, Yunnan, China;Yunnan Maternal and Child Health Care hospital, Yunnan, China;

关键词: Health related quality of life;    Pregnant women living with HIV;    EQ-5D;    SF-12;    Discrimination ability;    Construct validity;   

DOI  :  10.1186/s12955-017-0731-8

 received in 2016-10-24, accepted in 2017-07-28,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundThis paper investigates the properties and performance of the two generic measures, EQ-5D and SF-12, for Health-Related Quality of Life (HRQoL) assessments of pregnant women living with HIV in Kunming City, Yiliang County, Daguan County, Longchuan County, Tengchong County, Longling County and Fengqing County in Yunnan Province, China.MethodsAs part of a screening programme for the prevention of mother-to-child transmission of HIV (PMTCT), a retrospective cross-sectional survey was conducted in the seven Maternal and Infant Health Care centers in Yunnan Province, China, between April and June of 2016. The demographic and HIV infection-related information used in the study was collected through questionnaires designed by the study’s staff. HRQoL information was collected using two generic scales: EQ-5D and SF-12.ResultsA total sample of one hundred and one pregnant women with a mean age of 30.4 ± 5.1 years was investigated. Average time elapsed since infection diagnoses was 5.8 ± 3.4 years. Only one infant (1.0%) was HIV positive, and 56 (55.4%) infants were HIV negative. The HIV status of 44 (43.6%) infants was unknown. The relationship between the EQ-5D functional dimensions and the PCS-12 and the relationship between the EQ-5D anxiety/depression dimension and the MCS-12 were stronger. Those whose PCS-12 and MCS-12 scores were at the median or lower were classified as being in worse health, while those over the median were classified as being in better health. Respondents who reported no problem on each of the EQ-5D dimensions was divided according to the median SF-12 component scores. Those who scored at the median or lower than the median were classified as being in worse health, while those higher than the median were classified as being in better health. The VAS scores were also significantly different than the median split of the SF-12 scores for these subjects.ConclusionEQ-5D and SF-12 showed a discrimination ability in measuring the HRQoL of pregnant women living with HIV. The construct validity was identified for EQ-5D and SF-12 in the study. The respective constructs of EQ-5D and EQ-VAS may not overlap. Pregnant women living with HIV in the study gave more weight to their mental health when they provided a total health rating in EQ-VAS. EQ-VAS could explain the limitations of the EQ-5D dimension scores with ceiling effects in the survey. The results of our study could help to determine the suitable HRQoL instruments for pregnant women living with HIV and provide evidence for the proper comparison of EQ-5D and SF-12.

【 授权许可】

CC BY   
© The Author(s). 2017

【 图 表 】

Fig. 1

Fig. 1