Isolated pancreatic metastasis from rectal cancer: a case report and review of literature

World Journal of Surgical Oncology

Case Report

Ren-Chin Wu¹  Tsann-Long Hwang²  Yi-Yin Jan²  Ta-Sen Yeh²  Chao-Wei Lee²  Chun-Nan Yeh²  Miin-Fu Chen²  Jun-Te Hsu² 

[1] Department of Pathology, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan;Department of Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan;

关键词: Renal Cell Carcinoma;    Distal Pancreatectomy;    Pancreatic Resection;    Colorectal Adenocarcinoma;    Rectal Adenocarcinoma;   

DOI  :  10.1186/1477-7819-8-26

 received in 2009-11-27, accepted in 2010-04-07,  发布年份 2010

来源: Springer

【 摘 要 】

Isolated pancreatic metastases from a non-pancreatic primary malignancy are very rare. Studies have shown that resection of metastases is of proven benefit in some types of tumors. We report a case of 76-year-old Taiwanese woman with rectal adenocarcinoma treated with neoadjuvant chemoradiotherapy and abdominoperineal resection 2 years ago presenting with an asymptomatic mass at the pancreatic tail on a routine follow up abdominal computed tomography scan. The patient underwent distal pancreatectomy and splenectomy under the preoperative impression of a primary pancreatic malignancy. Histological examination of the surgical specimen showed metastatic adenocarcinoma. Immunohistochemical studies confirmed the diagnosis of pancreatic metastasis from rectal adenocarcinoma. Postoperative chemotherapy in the form of oral capecitabine was given. The patient is alive and disease free 12 months after the surgery. In a patient presenting with a pancreatic mass with history of a non-pancreatic malignancy, a differential diagnosis of pancreatic metastasis should be considered. Surgical resection of a solitary pancreatic mass is justified not only to get the definitive diagnosis but also to improve the survival.

【 授权许可】

Unknown   
© Lee et al; licensee BioMed Central Ltd. 2010. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.