期刊论文详细信息
BMC Cardiovascular Disorders
Secondary prevention strategies after an acute ST-segment elevation myocardial infarction in the AMI code era: beyond myocardial mechanical reperfusion
Research Article
Víctor Bazán1  Neus Salvatella2  Julio Martí-Almor2  Lluís Recasens2  Jordi Bruguera2  Oona Meroño2  Núria Ribas3  Cosme García-García4  Silvia Pérez-Fernández5  Roberto Elosua5 
[1] Cardiology Department, Hospital del Mar, Passeig Marítim, 25-29, 08003, Barcelona, Spain;Cardiology Department, Hospital del Mar, Passeig Marítim, 25-29, 08003, Barcelona, Spain;Heart Diseases Biomedical Research Group, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain;Cardiology Department, Hospital del Mar, Passeig Marítim, 25-29, 08003, Barcelona, Spain;Heart Diseases Biomedical Research Group, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain;Medicine Department, Program in Internal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain;Cardiology Department, Hospital del Mar, Passeig Marítim, 25-29, 08003, Barcelona, Spain;Hospital Universitari Germans Trias i Pujol, Badalona, Spain;IMIM (Hospital del Mar Medical Research Institute). Cardiovascular Epidemiology and Genetics Group (EGEC), REGICOR Study Group, Barcelona, Spain;CIBER de Enfermedades Cardiovasculares (CIBERCV), Barcelona, Spain;
关键词: ST-segment elevation myocardial infarction;    Coronary angioplasty;    Secondary prevention;    Prognosis;    Reperfusion therapy;    Cardiovascular risk factors;   
DOI  :  10.1186/s12872-017-0493-6
 received in 2016-11-23, accepted in 2017-02-03,  发布年份 2017
来源: Springer
PDF
【 摘 要 】

BackgroundThe AMI code is a regional network enhancing a rapid and widespread access to reperfusion therapy (giving priority to primary angioplasty) in patients with acute ST-segment elevation myocardial infarction (STEMI). We aimed to assess the long-term control of conventional cardiovascular risk factors after a STEMI among patients included in the AMI code registry.Design and methodsFour hundred and fifty-four patients were prospectively included between June-2009 and April-2013. Clinical characteristics were collected at baseline. The long-term control of cardiovascular risk factors and cardiovascular morbidity/mortality was assessed among the 6-months survivors.ResultsA total of 423 patients overcame the first 6 months after the STEMI episode, of whom 370 (87%) underwent reperfusion therapy (363, 98% of them, with primary angioplasty). At 1-year follow-up, only 263 (62%) had adequate blood pressure control, 123 (29%) had LDL-cholesterol within targeted levels, 126/210 (60%) smokers had withdrawn from their habit and 40/112 (36%) diabetic patients had adequate glycosylated hemoglobin levels. During a median follow-up of 20 (11–30) months, cumulative mortality of 6 month-survivors was 6.1%, with 9.9% of hospital cardiovascular readmissions. The lack of assessment of LDL and HDL-cholesterol were significantly associated with higher mortality and cardiovascular readmission rates.ConclusionsWhereas implementation of the AMI code resulted in a widespread access to rapid reperfusion therapy, its long-term therapeutic benefit may be partially counterbalanced by a manifestly suboptimal control of cardiovascular risk factors. Further efforts should be devoted to secondary prevention strategies after STEMI.

【 授权许可】

CC BY   
© The Author(s). 2017

【 预 览 】
附件列表
Files Size Format View
RO202311103440322ZK.pdf 733KB PDF download
【 参考文献 】
  • [1]
  • [2]
  • [3]
  • [4]
  • [5]
  • [6]
  • [7]
  • [8]
  • [9]
  • [10]
  • [11]
  • [12]
  • [13]
  • [14]
  • [15]
  • [16]
  • [17]
  • [18]
  • [19]
  • [20]
  • [21]
  • [22]
  • [23]
  • [24]
  • [25]
  • [26]
  • [27]
  • [28]
  • [29]
  • [30]
  • [31]
  • [32]
  • [33]
  • [34]
  • [35]
  • [36]
  • [37]
  • [38]
  • [39]
  • [40]
  文献评价指标  
  下载次数:0次 浏览次数:0次