Yeast processing bodies and stress granules: self-assembly ribonucleoprotein particles

Microbial Cell Factories

Commentary

Juana Díez¹  Mireia Giménez-Barcons¹ 

[1] Department of Experimental and Health Sciences, Universitat Pompeu Fabra, 08003, Barcelona, Spain;

关键词: processing bodies;    P-bodies;    stress granules;    RNA granules;   

DOI  :  10.1186/1475-2859-10-73

 received in 2011-08-04, accepted in 2011-09-24,  发布年份 2011

来源: Springer

【 摘 要 】

Processing bodies (PBs) and stress granules (SGs) are two highly conserved cytoplasmic ribonucleoprotein foci that contain translationally repressed mRNAs together with proteins from the mRNA metabolism. Interestingly, they also share some common features with other granules, including the prokaryotic inclusion bodies. Although the function of PBs and SGs remains elusive, major advances have been done in unraveling their composition and assembly by using the yeast Saccharomyces cerevisae.

【 授权许可】

CC BY   
© Giménez-Barcons and Díez; licensee BioMed Central Ltd. 2011