Socioeconomic inequities and hepatitis A virus infection in Western Brazilian Amazonian children: spatial distribution and associated factors

BMC Infectious Diseases

Research Article

Saulo A. S. Mantovani¹  Antonio C. Martins¹  Mônica da Silva-Nunes¹  Fernando L. C. C. Branco¹  Athos Muniz Braña¹  José A. Filgueira-Júnior¹  Thasciany M. Pereira¹  Andréia S. Guimarães¹  Alanderson A. Ramalho¹  Ana P. Santos¹  Breno Matos Delfino¹  Thiago S. Araújo¹  Rayanne A. Arruda¹  Humberto Oliart-Guzmán¹  Cristieli Sergio de Menezes Oliveira¹  Carlos H. M. L. Estrada²  Nancy Arróspide³  Cláudia T. Codeço⁴ 

[1] Centro de Ciências da Saúde e do Desporto, Universidade Federal do Acre. Campus Universitário, BR 364, Km 04, Bairro Distrito Industrial, Rio Branco, AC, Brazil;Dirección Regional de Salud de Madre de Dios, Av. Ernesto Rivero N° 475, Puerto Maldonado, Peru;Instituto Nacional de Salud, Cápac Yupanqui 1400 - Jesus María, 11, Lima, Peru;Scientific Computing Program, Avenida Brasil, 4365, Manguinhos, Rio de Janeiro, RJ, Brazil;

关键词: Hepatitis A;    Socioeconomic inequities;    Serology;    Spatial distribution;    Amazon;   

DOI  :  10.1186/s12879-015-1164-9

 received in 2015-03-25, accepted in 2015-09-30,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundHepatitis A is still a neglected health problem in the world. The most affected areas are the ones with disadvantaged socioeconomic conditions. In Brazil, seroprevalence studies showed that 64.7 % of the general population has antibodies against HAV (hepatitis A virus), and the Amazon region has the highest seroprevalence in the country.MethodsIn the present study the seroprevalence of total HAV antibodies in children between 1 and 5 years old residing in the urban area of Assis Brasil, Acre was measured and spatial distribution of several socioeconomic inequities was evaluated.ResultsIn the year of 2011, seroprevalence rate was 16.66 %. Factors associated with having a positive serology identified by multivariate analysis were being of indigenous ethnicity [adjusted Odds Ratio (aOR) = 3.27, CI 1.45–7.28], usage of water from the public system (aOR = 8.18, CI 1.07–62.53), living in a house not located in a street (aOR = 3.48, CI 1.54–7.87), and child age over 4 years old (aOR = 2.43, CI 1.23–4.79). The distribution of seropositive children was clustered in the eastern part of the city, where several socioeconomic inequities (lack of flushed toilets, lack of piped water inside the household and susceptibility of the household to flooding during rain, low maternal education, having wood or ground floor at home, and not owning a house, lack of piped water at home, and type of drinking water) also clustered.ConclusionsThe findings highlight that sanitation and water treatment still need improvement in the Brazilian Amazon, and that socioeconomic development is warranted in order to decrease this and other infectious diseases.

【 授权许可】

CC BY   
© Mantovani et al. 2015