Anti-Mullerian hormone is linked to the type of early pregnancy loss in idiopathic recurrent miscarriage: a retrospective cohort study

Reproductive Biology and Endocrinology

Short Communication

Sophie Pils¹  Natalia Stepien¹  Christine Kurz¹  Kazem Nouri¹  Johannes Ott²  Regina Promberger³ 

[1] Department of Gynecological Endocrinology and Reproductive Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria;Department of Gynecological Endocrinology and Reproductive Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria;Clinical Division of Gynecological Endocrinology and Reproductive Medicine, Medical University of Vienna, Waehringer Guertel 18-20, A-1090, Vienna, Austria;Department of Gynecological Endocrinology and Reproductive Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090, Vienna, Austria;Department of Obstetrics and Gynecology, Saint John of God Hospital Eisenstadt, Johannes von Gott-Platz 1, 7000, Eisenstadt, Austria;

关键词: Recurrent early pregnancy loss;    Recurrent miscarriage;    Ovarian reserve;    Anti-Mullerian hormone;    Follicle stimulating hormone;   

DOI  :  10.1186/s12958-017-0278-x

 received in 2017-06-01, accepted in 2017-07-25,  发布年份 2017

来源: Springer

【 摘 要 】

We correlated Anti-Mullerian hormone (AMH) levels and other parameters for ovarian reserve to the gestational age at the time of pregnancy loss in women with idiopathic recurrent miscarriage. In a retrospective study, 79 patients had suffered a total of 266 miscarriages. When comparing women with an “unembryonic” to those with an “embryonic” most recent miscarriage, there was no difference in median age (36.3 years, IQR 31.6–40.1 versus 34.2 years, IQR 29.9–38.0; p = 0.303) but in median AMH levels (0.7, IQR 0.2–18, versus median 1.8, IQR 1.3–3.3, respectively, p = 0.044) and in the rate of patients with an AMH ≤ 1 ng/mL (23/37, 62.2%, versus 8/42, 19%; p < 0.001). Thus, AMH might add to the diagnostic process in recurrent miscarriage in the future.

【 授权许可】

CC BY   
© The Author(s). 2017