A surgical approach in the treatment of preputial gland abscesses in mice

BMC Veterinary Research

Methodology Article

Aurelie A. Thomas¹  Henri G. M. J. Bertrand¹  Paul A. Flecknell²  Yvette C. Ellen³  Robert S. Dorward⁴ 

[1] Comparative Biology Centre, Newcastle University, Framlington Place, NE2 4HH, Newcastle Upon Tyne, UK;Comparative Biology Centre, Newcastle University, Framlington Place, NE2 4HH, Newcastle Upon Tyne, UK;Institute of Neurosciences, Newcastle University, Newcastle Upon Tyne, UK;Comparative Biology Centre, Newcastle University, Framlington Place, NE2 4HH, Newcastle Upon Tyne, UK;School of Veterinary Medicine and Science, Nottingham University, Nottingham, UK;School of Veterinary Medicine and Science, Nottingham University, Nottingham, UK;

关键词: Refinement;    Preputial;    Gland;    Surgery;    Abscess;   

DOI  :  10.1186/s12917-016-0636-5

 received in 2015-05-22, accepted in 2016-01-14,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundPreputial gland infection is a common occurrence in non-breeder male mice and can lead to abscesses. This report describes a surgical approach to treating and preventing this condition.ResultsSurgical removal of the glands was undertaken in 258 male C3H/HeNHsd mice. The glands were successfully removed in all of the animals with a low rate of post-surgery complications. Abscess recurrence due to incomplete gland resection occurred in 2.3 % of animals. Surgical wound opening (3.1 %) and infection of the surgical site (2.3 %) also occurred but were treated successfully.ConclusionIn the study described here, early intervention was successful in preventing intercurrent infection compromising both animal welfare and the outcome of the study.

【 授权许可】

CC BY   
© Bertrand et al. 2016