Cystic tumor of the liver without ovarian-like stroma or bile duct communication: two case reports and a review of the literature

World Journal of Surgical Oncology

Case Report

Akihisa Ueno¹  Akihiro Tanimoto¹  Yoko Fujii-Nishimura²  Michiie Sakamaoto²  Yohei Masugi²  Taizo Hibi³  Yuta Abe³  Minoru Kitago³  Hiroshi Yagi³  Yuko Kitagawa³  Masahiro Shinoda³  Norihiro Kishida³  Osamu Itano³  Minoru Tanabe⁴ 

[1]Department of Diagnostic Radiology, Keio University, School of Medicine, 35 Shinanomachi, 160-8582, Shinjuku-ku, Tokyo, Japan

[2]Department of Pathology, Keio University, School of Medicine, 35 Shinanomachi, 160-8582, Shinjuku-ku, Tokyo, Japan

[3]Department of Surgery, Keio University, School of Medicine, 35 Shinanomachi, 160-8582, Shinjuku-ku, Tokyo, Japan

[4]Department of Surgery, Tokyo Medical and Dental University, 1-5-45 Yushima, 113-8519, Bunkyo-ku, Tokyo, Japan

关键词: Cystic neoplasm;    Liver;    Ovarian-like stroma;    Bile duct communication;    Mucinous cystic neoplasm;    Intraductal papillary neoplasm of bile duct;   

DOI  :  10.1186/1477-7819-12-229

 received in 2013-11-17, accepted in 2014-07-04,  发布年份 2014

来源: Springer

【 摘 要 】

We report two cases of cystic neoplasm of the liver with mucinous epithelium in which both ovarian-like stroma and bile duct communication were absent. The first case was a 41-year-old woman. She underwent right trisegmentectomy due to a multilocular cystic lesion, 15 cm in diameter, with papillary nodular components in the medial segment and right lobe. Histologically, arborizing papillae were seen in the papillary lesion. The constituent neoplastic cells had sufficient cytoarchitectural atypia to be classified as high-grade dysplasia. The second case was a 60-year-old woman. She underwent left lobectomy due to a unilocular cystic lesion, 17 cm in diameter, in the left lobe. Histologically, the cyst wall was lined by low columnar epithelia with slight cellular atypia. In both cases, neither ovarian-like stroma nor bile duct communications were found throughout the resected specimen. According to the most recent World Health Organization (WHO) classification in 2010, cystic tumors of the liver with mucinous epithelium are classified as mucinous cystic neoplasms when ovarian-like stromata are found, and as intraductal papillary neoplasm of bile duct when bile duct communication exists. Therefore, we diagnosed the cystic tumors as ‘biliary cystadenoma’ according to the past WHO classification scheme from 2000. We believe that the combined absence of both ovarian-like stroma and bile duct communication is possible in mucinous cystic tumors of the liver. Herein, we have described the clinicopathologic features of the two cases and reviewed past cases in the literature.

【 授权许可】

Unknown   
© Kishida et al.; licensee BioMed Central Ltd. 2014. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.