Factors associated with anxiety and depression in men undergoing fertility investigations: a cross-sectional study

BMC Psychology

Research

Dhekra Chebil¹  Ines Boughzela²  Tesnim Ajina²  Rim Kooli²  Manel Boussabbeh³  Meriem Mehdi⁴  Amira Sallem⁴  Soumaya Mougou⁵  Bochra Ben Mohamed⁶ 

[1] Faculty of Medicine of Sousse, University of Sousse, Sousse, Tunisia;Laboratory of Cytogenetics and Reproductive Biology, Maternity and Neonatology Center, Fattouma Bourguiba University Teaching Hospital, Monastir, Tunisia;Laboratory of Cytogenetics and Reproductive Biology, Maternity and Neonatology Center, Fattouma Bourguiba University Teaching Hospital, Monastir, Tunisia;Laboratory for Research On Biologically Compatible Substances, Faculty of Dentistry of Monastir, University of Monastir, Monastir, Tunisia;Laboratory of Cytogenetics and Reproductive Biology, Maternity and Neonatology Center, Fattouma Bourguiba University Teaching Hospital, Monastir, Tunisia;Laboratory of Histology-Embryology and Cytogenetics (LR 18 ES 40), Faculty of Medicine of Monastir, University of Monastir, Monastir, Tunisia;Laboratory of Human Cytogenetics and Reproductive Biology, Farhat Hached Univesity Teaching Hospital, Sousse, Tunisia;Psychiatry Service, Fattouma Bourguiba University Teaching Hospital, Monastir, Tunisia;

关键词: Anxiety;    Depression;    Male infertility;    Semen analysis;    Tunisia;   

DOI  :  10.1186/s40359-023-01330-z

 received in 2023-01-12, accepted in 2023-09-14,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundInfertility is a real public health issue because of its medical, socio-cultural, and financial impact. It does also have heavy psychological consequences on both partners. This study aimed to assess levels of anxiety and depression among men undergoing infertility investigation and to identify their associated factors.MethodsWe conducted a cross-sectional study in the Laboratory of Cytogenetics and Reproductive Biology of Fattouma Bourguiba University Teaching Hospital (Monastir, Tunisia) between August 30th, 2020, and March 16th, 2021. Anxiety and depression levels were assessed using the valid Arab version of the Hospital Anxiety and Depression scale (HAD). Semen parameters were analyzed and interpreted according to 2021 World Health Organization (WHO) guidelines.ResultsA total of 282 men were included in the current study. The mean HAD-D (depression) and HAD-A (anxiety) scores were of 6.56 ± 3.07 (IQR [4–8]) and 7.94 ± 3.73 (IQR[5–10]) respectively. Univariate analysis showed that patients having two or more comorbidities were nearly five times more likely to be anxious than those without or with only one comorbidity (ORc = 4.71; p = 0.007). Furthermore, single patients were about four times more anxious than those in couple having primary or secondary infertility (ORc = 3.85; p = 0.027). With regards to semen parameters, patients having hypospermia were more than two times anxious compared with those with normal semen volume (ORc = 2.33; p = 0.034). As for depression, we observed that patients with an infertility history lasting for a year or more have a nine times greater risk of depression (ORc = 9.848; p = 0.007). With regards to semen parameters, patients exhibiting two or more semen abnormalities, teratozoospermia and increased MAI were more depressed (ORc = 2.478; p = 0.036; ORc = 2.549: p = 0.023; ORc = 2.762; p = 0.036). Furthermore, we found a negative correlation between HAD-A scores and patient’s age.ConclusionsWe pointed out through the current study the associated factors with anxiety and depression in patients under fertility management to precociously identify those who need psychological counseling and hence to better manage infertility issues.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

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