Individual and household characteristics of persons with Plasmodium falciparum malaria in sites with varying endemicities in Kinshasa Province, Democratic Republic of the Congo

Malaria Journal

Research

Steven R. Meshnick¹  Lauren Levitz¹  Kyaw L. Thwai¹  Melchior Kashamuka Mwandagalirwa²  Margaret Carrel³  Michael Emch⁴  Varun Goel⁴  Jonathan B. Parr⁵  Antoinette Tshefu⁶  Mark Janko⁷ 

[1] Department of Epidemiology, University of North Carolina-Chapel Hill, CB7435, McGavran-Greenberg Hall, 27599, Chapel Hill, NC, USA;Department of Epidemiology, University of North Carolina-Chapel Hill, CB7435, McGavran-Greenberg Hall, 27599, Chapel Hill, NC, USA;Ecole de Sante Publique, Faculte de Medecine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo;Department of Geographical & Sustainability Sciences, University of Iowa, 305 Jessup Hall, 52245, Iowa City, IA, USA;Department of Geography, CB3220, University of North Carolina-Chapel Hill, 27599, Chapel Hill, NC, USA;Division of Infectious Diseases, School of Medicine, University of North Carolina-Chapel Hill, 130 Mason Farm Road, 27599, Chapel Hill, NC, USA;Ecole de Sante Publique, Faculte de Medecine, University of Kinshasa, Kinshasa, Democratic Republic of the Congo;Global Health Institute, Duke University, 229 Trent Hall, 27710, Durham, NC, USA;

关键词: Malaria;    Democratic Republic of the Congo;    Longitudinal study;    Surveillance;    RDT;    PCR;   

DOI  :  10.1186/s12936-017-2110-7

 received in 2017-08-28, accepted in 2017-11-06,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundThe Democratic Republic of the Congo (DRC) bears a large share of global malaria burden despite efforts to control and eliminate the disease. More detailed understanding of individual and household level characteristics associated with malaria are needed, as is an understanding of how these characteristics vary spatiotemporally and across different community-level malaria endemicities. An ongoing study in Kinshasa Province is designed to address gaps in prior malaria surveillance in the DRC by monitoring malaria across seasons, age groups and in high and low malaria sites. Across seven sites, 242 households and 1591 individuals are participating in the study. Results of the enrollment questionnaire, rapid diagnostic tests and PCR testing of dried blood spots are presented.ResultsOverall malaria prevalence in the study cohort is high, 27% by rapid diagnostic test and 31% by polymerase chain reaction, and malaria prevalence is highly varied across very small geographic distances. Malaria prevalence is highest in children aged 6–15. While the majority of households own bed nets, bed net usage is less than 50%.ConclusionsThe study cohort will provide an understanding of how malaria persists in populations that have varying environmental exposures, varying community-level malaria, and varying access to malaria control efforts.

【 授权许可】

CC BY   
© The Author(s) 2017