Clinical outcome of laparoscopic complete mesocolic excision in the treatment of right colon cancer

World Journal of Surgical Oncology

Research

Chuan Zhang¹  Zan Fu¹  Dongsheng Zhang¹  Yueming Sun¹  Yong Wang¹ 

[1] Department of Colorectal, the First Affiliated Hospital of Nanjing Medical University, 210029, Nanjing, Jiangsu, China;

关键词: Complete mesocolic excision;    Laparoscopy;    Right colon cancer;   

DOI  :  10.1186/s12957-017-1236-y

 received in 2017-05-21, accepted in 2017-08-19,  发布年份 2017

来源: Springer

【 摘 要 】

BackgroundThis study aimed to investigate the clinical outcome of complete mesocolic excision (CME) with a caudal-to-cranial medial approach in the treatment of right colon cancer.MethodsThe clinical data of 172 patients who underwent laparoscopic CME for right colon cancer and were admitted to the First Affiliated Hospital of Nanjing Medical University from January 2010 to April 2015 were retrospectively analyzed. The 3-year disease-free survival (DFS) and overall survival (OS) in relation to gender, age, history of abdominal surgery, tumor size, complications, and tumor–node–metastasis (TNM) classification were analyzed using the Kaplan–Meier survival curves.ResultsA total of 172 patients with 94 males and 78 females were included. The average surgical time was 113.5 ± 34.4 min, blood loss was 74.2 ± 28.1 mL, and the number of lymph nodes retrieved was 23.3 ± 9.2. No readmission or death occurred within 30 days after surgery. Postoperative complications occurred in 16.3% of the patients, which included wound infection (3 patients), chylous fistula (22 patients), anastomotic leakage (1 patient), anastomotic bleeding (1 patient), and lung infection (1 patient). The 3-year DFS and OS were 81.7 and 89.1%, respectively. The rate of DFS and OS was significantly higher in stages I and II compared with that in stage III (P < 0.05), and in stages IIIA and IIIB compared with that in stage IIIC (P < 0.05).ConclusionsLaparoscopic CME with a caudal-to-cranial medial approach in the treatment of right colon cancer had good short-term efficacy and satisfactory oncological outcome.

【 授权许可】

CC BY   
© The Author(s). 2017