Efficacy of four different hemostatic agents in thyroid surgery in reducing the amount of post-operative fluid collection

BMC Surgery

Research

Sonja Militz-Müller¹  Thomas von Ahnen¹  Martin von Ahnen¹  Anna Süß¹  Hans-Martin Schardey¹  Ulrich Wirth²  Josefine Schardey²  Stefan Schopf³ 

[1] Krankenhaus Agatharied GmbH, Hausham, Germany;Ludwig-Maximilians-Universität München, München, Germany;RoMed Klinik Bad Aibling, Bad Aibling, Germany;

关键词: Postoperative bleeding;    Hemostatic agents;    Thyroid surgery;    Drainage volume;   

DOI  :  10.1186/s12893-023-02172-7

 received in 2023-07-03, accepted in 2023-08-25,  发布年份 2023

来源: Springer

【 摘 要 】

PurposesPostoperative bleeding remains a life-threatening complication in thyroid surgery. The aim was to assess the efficacy of four different hemostatic agents, Collagen-Fibrinogen-Thrombin Patch (CFTP) in two sizes (3 × 2.5 cm and 9.5 × 4.8 cm), polysaccharide particles (1 g) and Cellulose Gauze (2.5 × 5 cm) on postoperative drainage volume (DV) compared to a control group.MethodsWe included from October 2007 until Mai 2011, 150 patients (30 per group) for this monocentric, retrospective case-controlled study. Patients were scheduled for a hemithyroidectomy or thyroidectomy. The primary endpoint was the postoperative DV within the first 24 h, secondary the incidence of adverse events.ResultsThere were no difference in demographic parameters. The mean DV (± SD) was 51.15 (± 36.86) ml in the control, 50.65 (± 42.79) ml in small (3 × 2.5 cm), 25.38 (± 23.99) ml in large CFTP (9.5 × 4.8 cm), 53.11 (± 39.48) ml in the polysaccharide particles and 48.94 (± 30.59) ml in the cellulose gauze group. DV was significantly reduced with the large CFTP (p < 0.05) compared to all other groups. There were no adverse events.ConclusionsWe were able to demonstrate a significant reduction in the DV for the large CFTP group compared to the other collectives. Although this as being associated with not inconsiderable costs and we would only recommend its use for high-risk patients only.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

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