Mitochondrial dynamics: quantifying mitochondrial fusion in vitro

BMC Biology

Commentary

Jean-Claude Martinou¹  Alexis Jourdain¹ 

[1] Department of Cell Biology, University of Geneva, Quai Ernest-Ansermet 30, 1211, Geneva 4, Switzerland;

关键词: Outer Membrane;    Mitochondrial Fission;    Mitochondrial Dynamic;    Mitochondrial Fusion;    Coelenterazine;   

DOI  :  10.1186/1741-7007-8-99

 received in 2010-07-07, accepted in 2010-07-16,  发布年份 2010

来源: Springer

【 摘 要 】

Mitochondrial fusion is an essential process for preserving the integrity and stability of mitochondrial DNA; however, regulation of this process remains largely mysterious. In this issue of BMC Biology, Schauss and colleagues describe a simple, reliable, and robust novel assay that allows fusion of mammalian mitochondria to be quantified in vitro.See research article: http://biomedcentral.com/1741-7007/8/100

【 授权许可】

CC BY   
© Jourdain and Martinou; licensee BioMed Central Ltd. 2010