Clear cell carcinoma arising from abdominal wall endometriosis: a unique case with bladder and lymph node metastasis

World Journal of Surgical Oncology

Case Report

Jinghua Leng¹  Jinghe Lang¹  Haiyuan Liu¹  Quancai Cui² 

[1] Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, China;Department of Pathology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing, China;

关键词: Endometriosis;    Malignant Transformation;    Clear Cell Carcinoma;    Inguinal Lymph Node;    Lymph Metastasis;   

DOI  :  10.1186/1477-7819-12-51

 received in 2013-09-10, accepted in 2014-02-12,  发布年份 2014

来源: Springer

【 摘 要 】

The malignant transformation of abdominal wall endometriosis is a rare event and poorly understood. Less than 30 cases have been reported in the literature. Most of the reported cases have a solitary tumor in the abdominal scar. A few cases have metastasis. Here we report a case of clear cell carcinoma in abdominal wall endometriosis with bladder and lymph system metastasis. The patient had a history of abdominal wall endometriosis and recently developed symptoms of urgent urination and inguinal mass. Physical examination and a computed tomography (CT) scan detected lymph node metastasis. CT and cystoscopy confirmed bladder involvement. The patient underwent extensive surgery and chemotherapy. Pathological analysis made a diagnosis of clear cell carcinoma with bladder and lymph node metastasis. The patient was followed up and died of the disease. Symptoms of bladder invasion and lymph node spread could be a sign of malignant transformation. Local invasion and lymph node spread are two important forms of tumor metastasis. Extensive lymph nodes metastasis might be related with poor prognosis.

【 授权许可】

CC BY   
© Liu et al.; licensee BioMed Central Ltd. 2014