SIRT4 controls the balance between lipid synthesis and catabolism by repressing malonyl-CoA decarboxylase

BMC Proceedings

Poster Presentation

Clemens Steegborn¹  Frank Fischer¹  Gina Boanca¹  Noah Dephoure²  Steven P Gygi²  Natalie J German³  Gaëlle Laurent³  Vincent CJ de Boer⁴  Bhavapriya Vaitheesvaran⁵  Irwin J Kurland⁵  Michael Davies⁶  Deborah M Muoio⁶  Asish K Saha⁷  Neil B Ruderman⁷ 

[1] Department of Biochemistry, University of Bayreuth, 95447, Bayreuth, Germany;Department of Cell Biology, Harvard University Medical School, 02115, Boston, MA, USA;Department of Cell Biology, The Paul F. Glenn Labs for the Biological Mechanisms of Aging, Harvard Medical School, 02115, Boston, MA, USA;Department of Cell Biology, The Paul F. Glenn Labs for the Biological Mechanisms of Aging, Harvard Medical School, 02115, Boston, MA, USA;Laboratory Genetic Metabolic Diseases, Academic Medical Center, 1105AZ, Amsterdam, The Netherlands;Department of Medicine, Diabetes Center, Stable Isotope and Metabolomics Core Facility, Albert Einstein College of Medicine, 10461, Bronx, New York, USA;Departments of Medicine and Pharmacology & Cancer Biology, Sarah W. Stedman Nutrition and Metabolism Center, Duke University Medical Center, NC27710, Durham, USA;Diabetes Research Unit, Section of Endocrinology, Department of Medicine, Boston University Medical Center, 02118, Boston, MA, USA;

关键词: Lipid;    Adipose Tissue;    Lipid Metabolism;    Acid Oxidation;    Fatty Acid Oxidation;   

DOI  :  10.1186/1753-6561-6-S3-P30

来源: Springer

【 授权许可】

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© Laurent et al; licensee BioMed Central Ltd. 2012. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.