Use of testosterone alone as hormonal male contraceptive

Basic and Clinical Andrology

Revue/Review

E. Nieschlag¹ 

[1] Centre of Reproductive Medicine and Andrology of the University of Münster, WHO Collaboration Centre for Research in Male Reproduction, Domagkstrasse 11, D-40129, Münster, Germany;

关键词: World population;    Family planning;    Male contraception;    Spermatogenesis suppression;    Testosterone preparations;    Synthetic androgens;    Population mondiale;    Planification familiale;    Contraception masculine;    Suppression de la spermatogenèse;    Formes de testostérone;    Androgènes de synthèse;   

DOI  :  10.1007/s12610-012-0187-y

 received in 2012-03-07, accepted in 2012-05-25,  发布年份 2012

来源: Springer

【 摘 要 】

The world population continues to grow rapidly while resources for sustainable living dwindle and manmade ecological problems increase proportionally to the overpopulation. Family planning is required to reduce population growth in developing countries and to stabilize populations in developed countries. Contraception makes abortion superfluous and provides the key to family planning. Women increasingly demand that men share the burden and risks of contraception and — as opinion polls show — men would be willing to use contraceptives if they were available. Research has established the principle of hormonal male contraception based on suppression of gonadotropins and spermatogenesis. All hormonal male contraceptives use testosterone, but in East Asian men, testosterone alone can suppress spermatogenesis to a level compatible with contraceptive protection. In Caucasians additional agents are required of which progestins are favoured.

【 授权许可】

Unknown   
© SALF et Springer-Verlag France 2012