Repaired tetralogy of Fallot: the roles of cardiovascular magnetic resonance in evaluating pathophysiology and for pulmonary valve replacement decision support

Journal of Cardiovascular Magnetic Resonance

Review

Tal Geva¹ 

[1] Department of Cardiology, Children's Hospital Boston, Department of Pediatrics, Harvard Medical School, Boston, MA, USA;

关键词: Right Ventricular;    Cardiovascular Magnetic Resonance;    Late Gadolinium Enhancement;    Pulmonary Valve;    Right Ventricular Outflow Tract;   

DOI  :  10.1186/1532-429X-13-9

 received in 2010-12-08, accepted in 2011-01-20,  发布年份 2011

来源: Springer

【 摘 要 】

Surgical management of tetralogy of Fallot (TOF) results in anatomic and functional abnormalities in the majority of patients. Although right ventricular volume load due to severe pulmonary regurgitation can be tolerated for many years, there is now evidence that the compensatory mechanisms of the right ventricular myocardium ultimately fail and that if the volume load is not eliminated or reduced by pulmonary valve replacement the dysfunction might be irreversible. Cardiovascular magnetic resonance (CMR) has evolved during the last 2 decades as the reference standard imaging modality to assess the anatomic and functional sequelae in patients with repaired TOF. This article reviews the pathophysiology of chronic right ventricular volume load after TOF repair and the risks and benefits of pulmonary valve replacement. The CMR techniques used to comprehensively evaluate the patient with repaired TOF are reviewed and the role of CMR in supporting clinical decisions regarding pulmonary valve replacement is discussed.

【 授权许可】

CC BY   
© Geva; licensee BioMed Central Ltd. 2011