BMC Infectious Diseases | |
Early-onset ventilator-associated pneumonia incidence in intensive care units: a surveillance-based study | |
Research Article | |
Jean-Marie Januel1  Philippe Vanhems2  Thomas Bénet2  Nicolas Voirin2  | |
[1] Health Care Evaluation Unit, Institute of Social and Preventive Medicine-IUMSP, University of Lausanne, Lausanne, Switzerland;Hospices Civils de Lyon, Infection Control Unit, Edouard Herriot Hospital, Lyon, France;Laboratory of Epidemiology and Public Health, CNRS UMR 5558, University of Lyon, University of Lyon 1, Lyon, France; | |
关键词: Intensive Care Unit; Intensive Care Unit Admission; Intensive Care Unit Patient; Intensive Care Unit Stay; Aspiration Pneumonia; | |
DOI : 10.1186/1471-2334-11-236 | |
received in 2011-03-23, accepted in 2011-09-06, 发布年份 2011 | |
来源: Springer | |
【 摘 要 】
BackgroundThe incidence of ventilator-associated pneumonia (VAP) within the first 48 hours of intensive care unit (ICU) stay has been poorly investigated. The objective was to estimate early-onset VAP occurrence in ICUs within 48 hours after admission.MethodsWe analyzed data from prospective surveillance between 01/01/2001 and 31/12/2009 in 11 ICUs of Lyon hospitals (France). The inclusion criteria were: first ICU admission, not hospitalized before admission, invasive mechanical ventilation during first ICU day, free of antibiotics at admission, and ICU stay ≥ 48 hours. VAP was defined according to a national protocol. Its incidence was the number of events per 1,000 invasive mechanical ventilation-days. The Poisson regression model was fitted from day 2 (D2) to D8 to incident VAP to estimate the expected VAP incidence from D0 to D1 of ICU stay.ResultsTotally, 367 (10.8%) of 3,387 patients in 45,760 patient-days developed VAP within the first 9 days. The predicted cumulative VAP incidence at D0 and D1 was 5.3 (2.6-9.8) and 8.3 (6.1-11.1), respectively. The predicted cumulative VAP incidence was 23.0 (20.8-25.3) at D8. The proportion of missed VAP within 48 hours from admission was 11% (9%-17%).ConclusionsOur study indicates underestimation of early-onset VAP incidence in ICUs, if only VAP occurring ≥ 48 hours are considered to be hospital-acquired. Clinicians should be encouraged to develop a strategy for early detection after ICU admission.
【 授权许可】
CC BY
© Vanhems et al; licensee BioMed Central Ltd. 2011
【 预 览 】
Files | Size | Format | View |
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RO202311101651792ZK.pdf | 175KB | download |
【 参考文献 】
- [1]
- [2]
- [3]
- [4]
- [5]
- [6]
- [7]
- [8]
- [9]
- [10]
- [11]
- [12]
- [13]
- [14]
- [15]
- [16]
- [17]
- [18]
- [19]
- [20]
- [21]
- [22]