Mitochondrial haplogroup N1a phylogeography, with implication to the origin of European farmers

BMC Evolutionary Biology

Research Article

Tapas Kumar Chaudhuri¹  Miroslava Derenko²  Boris Malyarchuk²  Cai-Ling Zhang³  Bikash Mitra⁴  Malliya Gounder Palanichamy⁵  Ya-Ping Zhang⁵ 

[1] Cellular Immunology Laboratory, Department of Zoology, University of North Bengal, 734013, SiliguriWest Bengal, India;Institute of Biological Problems of the North, Far-East Branch of the Russian Academy of Sciences, 685000, Magadan, Russia;Laboratory for Conservation and Utilization of Bio-resources, Yunnan University, 2 North Green Lake Street, 650091, Kunming, China;Laboratory for Conservation and Utilization of Bio-resources, Yunnan University, 2 North Green Lake Street, 650091, Kunming, China;Cellular Immunology Laboratory, Department of Zoology, University of North Bengal, 734013, SiliguriWest Bengal, India;Laboratory for Conservation and Utilization of Bio-resources, Yunnan University, 2 North Green Lake Street, 650091, Kunming, China;State Key Laboratory of Genetic resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, 650223, Kunming, China;

关键词: Arabian Peninsula;    Coalescence Time;    Farm Sample;    FLO1 Lineage;    Neolithic Farmer;   

DOI  :  10.1186/1471-2148-10-304

 received in 2010-03-31, accepted in 2010-10-12,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundTracing the genetic origin of central European farmer N1a lineages can provide a unique opportunity to assess the patterns of the farming technology spread into central Europe in the human prehistory. Here, we have chosen twelve N1a samples from modern populations which are most similar with the farmer N1a types and performed the complete mitochondrial DNA genome sequencing analysis. To assess the genetic and phylogeographic relationship, we performed a detailed survey of modern published N1a types from Eurasian and African populations.ResultsThe geographic origin and expansion of farmer lineages related N1a subclades have been deduced from combined analysis of 19 complete sequences with 166 N1a haplotypes. The phylogeographic analysis revealed that the central European farmer lineages have originated from different sources: from eastern Europe, local central Europe, and from the Near East via southern Europe.ConclusionsThe results obtained emphasize that the arrival of central European farmer lineages did not occur via a single demic diffusion event from the Near East at the onset of the Neolithic spread of agriculture into Europe. Indeed these results indicate that the Neolithic transition process was more complex in central Europe and possibly the farmer N1a lineages were a result of a 'leapfrog' colonization process.

【 授权许可】

CC BY   
© Palanichamy et al; licensee BioMed Central Ltd. 2010