Coronary artery size and origin imaging in children: a comparative study of MRI and trans-thoracic echocardiography

BMC Medical Imaging

Research Article

Karolina Bilska¹  Sujeev Mathur¹  Markus Henningsson²  Rene M. Botnar²  John Simpson³  Israel Valverde³  Sarah A. Peel³  Gerald F. Greil⁴  Tarique Hussain⁴ 

[1]Department of Paediatric Cardiology, Evelina London Children’s Hospital, Guy’s & St Thomas’ NHS Foundation Trust, Westminster Bridge Road, London, UK

[2]Division of Imaging Sciences, King’s College London, NIHR Biomedical Research Centre at Guy’s & St Thomas’ NHS Foundation Trust, London, UK

[3]Division of Imaging Sciences, King’s College London, NIHR Biomedical Research Centre at Guy’s & St Thomas’ NHS Foundation Trust, London, UK

[4]Department of Paediatric Cardiology, Evelina London Children’s Hospital, Guy’s & St Thomas’ NHS Foundation Trust, Westminster Bridge Road, London, UK

[5]Division of Imaging Sciences, King’s College London, NIHR Biomedical Research Centre at Guy’s & St Thomas’ NHS Foundation Trust, London, UK

[6]Department of Paediatric Cardiology, Evelina London Children’s Hospital, Guy’s & St Thomas’ NHS Foundation Trust, Westminster Bridge Road, London, UK

[7]Department of Pediatrics, UT Southwestern Medical Center, Children’s Medical Center, 1935 Medical District Drive, Dallas, TX, USA

关键词: Child;    Infant;    Newborn;    Adolescent;    Magnetic resonance imaging;    Echocardiography;    Coronary vessels;   

DOI  :  10.1186/s12880-015-0095-7

 received in 2014-10-24, accepted in 2015-10-22,  发布年份 2015

来源: Springer

【 摘 要 】

BackgroundThe purpose of this study was to see how coronary magnetic resonance angiography (CMRA) compared to echocardiography for the detection of coronary artery origins and to compare CMRA measurements for coronary dimensions in children with published echocardiographic reference values.MethodsEnrolled patients underwent dual cardiac phase CMRA and echocardiography under the same anesthetic. Echocardiographic measurements of the right coronary artery (RCA), left anterior descending (LAD) and left main (LM) were made. CMRA dimensions were assessed manually at the same points as the echocardiographic measurements. The number of proximal LAD branches imaged was also recorded in order to give an estimate of distal coronary tree visualization.ResultsFifty patients (24 boys, mean age 4.0 years (range 18 days to 18 years)) underwent dual-phase CMRA. Coronary origins were identified in 47/50 cases for CMRA (remaining 3 were infants aged 3, 9 and 11 months). In comparison, origins were identified in 41/50 cases for echo (remaining were all older children).CMRA performed better than echocardiography in terms of distal visualization of the coronary tree (median 1 LAD branch vs. median 0; p = 0.001).Bland-Altman plots show poor agreement between echocardiography and CMRA for coronary measurements. CMRA measurements did vary according to cardiac phase (systolic mean 1.90, s.d. 0.05 mm vs. diastolic mean 1.84, s.d. 0.05 mm; p = 0.002).ConclusionsDual-phase CMRA has an excellent (94 %) success rate for the detection of coronary origins in children. Newborn infants remain challenging and echocardiography remains the accepted imaging modality for this age group. Echocardiographic reference ranges are not applicable to CMRA measurements as agreement was poor between modalities. Future coronary reference values, using any imaging modality, should quote the phase in which it was measured.

【 授权许可】

CC BY   
© Hussain et al. 2015