Assessment of the right ventricle with cardiovascular magnetic resonance at 7 Tesla

Journal of Cardiovascular Magnetic Resonance

Research

Andreas Graessl¹  Fabian Hezel¹  Lukas Winter¹  Jan Rieger¹  Christof Thalhammer¹  Matthias A Dieringer²  Valeriy Tkachenko²  Florian von Knobelsdorff-Brenkenhoff²  Jeanette Schulz-Menger²  Thoralf Niendorf³ 

[1] Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine, Berlin, Germany;Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine, Berlin, Germany;Department of Cardiology and Nephrology, Working Group on Cardiovascular Magnetic Resonance, Experimental and Clinical Research Center, a joint cooperation between the Charité Medical Faculty and the Max-Delbrueck Center for Molecular Medicine, HELIOS Klinikum Berlin Buch, Berlin, Germany;Berlin Ultrahigh Field Facility (B.U.F.F.), Max-Delbrueck Center for Molecular Medicine, Berlin, Germany;Experimental and Clinical Research Center, a joint cooperation between the Charité Medical Faculty and the Max-Delbrueck Center for Molecular Medicine, Berlin, Germany;

关键词: Magnetic resonance imaging;    Right ventricle;    Ultrahigh field;    Cardiac;   

DOI  :  10.1186/1532-429X-15-23

 received in 2012-10-17, accepted in 2013-03-06,  发布年份 2013

来源: Springer

【 摘 要 】

BackgroundFunctional and morphologic assessment of the right ventricle (RV) is of clinical importance. Cardiovascular magnetic resonance (CMR) at 1.5T has become gold standard for RV chamber quantification and assessment of even small wall motion abnormalities, but tissue analysis is still hampered by limited spatial resolution. CMR at 7T promises increased resolution, but is technically challenging. We examined the feasibility of cine imaging at 7T to assess the RV.MethodsNine healthy volunteers underwent CMR at 7T using a 16-element TX/RX coil and acoustic cardiac gating. 1.5T served as gold standard. At 1.5T, steady-state free-precession (SSFP) cine imaging with voxel size (1.2x1.2x6) mm3 was used; at 7T, fast gradient echo (FGRE) with voxel size (1.2x1.2x6) mm3 and (1.3x1.3x4) mm3 were applied. RV dimensions (RVEDV, RVESV), RV mass (RVM) and RV function (RVEF) were quantified in transverse slices. Overall image quality, image contrast and image homogeneity were assessed in transverse and sagittal views.ResultsAll scans provided diagnostic image quality. Overall image quality and image contrast of transverse RV views were rated equally for SSFP at 1.5T and FGRE at 7T with voxel size (1.3x1.3x4)mm3. FGRE at 7T provided significantly lower image homogeneity compared to SSFP at 1.5T. RVEDV, RVESV, RVEF and RVM did not differ significantly and agreed close between SSFP at 1.5T and FGRE at 7T (p=0.5850; p=0.5462; p=0.2789; p=0.0743). FGRE at 7T with voxel size (1.3x1.3x4) mm3 tended to overestimate RV volumes compared to SSFP at 1.5T (mean difference of RVEDV 8.2±9.3ml) and to FGRE at 7T with voxel size (1.2x1.2x6) mm3 (mean difference of RVEDV 9.3±8.6ml).ConclusionsFGRE cine imaging of the RV at 7T was feasible and provided good image quality. RV dimensions and function were comparable to SSFP at 1.5T as gold standard.

【 授权许可】

Unknown   
© von Knobelsorff-Brenkenhoff et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.