Economic burden of vulvar and vaginal intraepithelial neoplasia: retrospective cost study at a German dysplasia centre

BMC Infectious Diseases

Research Article

Eduard Huppertz¹  Patrick Kok²  Sarah Schmitter³  Monika Hampl⁴  Olaf Schulz-Holstege⁴ 

[1] Im Sand 4, 56412, Niedererbach, Germany;Institut für Experimentelle Psychologie, Heinrich-Heine-Universtität, Universitätsstr. 1, 40225, Düsseldorf, Germany;Sanofi Pasteur MSD GmbH, Paul-Ehrlich-Straße 1, 69181, Leimen, Germany;Universitätsfrauenklinik Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany;

关键词: Indirect Cost;    Sick Leave;    Cervical Intraepithelial Neoplasia;    Diagnostic Purpose;    Direct Medical Cost;   

DOI  :  10.1186/1471-2334-11-73

 received in 2010-06-23, accepted in 2011-03-22,  发布年份 2011

来源: Springer

【 摘 要 】

BackgroundHuman papillomavirus is responsible for a variety of diseases including grade 2 and 3 vulvar and vaginal intraepithelial neoplasia. The aim of this study was to assess parts of the burden of the last diseases including treatment costs. The direct medical resource use and cost of surgery associated with neoplasia and related diagnostic procedures (statutory health insurance perspective) were estimated, as were the indirect costs (productivity losses) associated with surgical treatment and related gynaecology visits for diagnostic purposes.MethodsData from 1991-2008 were retrospectively collected from patient records of the outpatient unit of the Gynaecological Dysplasia Clinic, Heinrich Heine University, Dusseldorf, Germany. Two subgroups of patients were analysed descriptively: women undergoing one surgical procedure related to a diagnosis of vulvar and/or vaginal intraepithelial neoplasia, and women undergoing two or more surgical procedures. Target measures were per-capita medical resource consumption, direct medical cost and indirect cost.ResultsOf the 94 women analysed, 52 underwent one surgical intervention and 42 two or more interventions (mean of 3.0 interventions during the total period of analysis). Patients undergoing one surgical intervention accrued €881 in direct costs and €682 in indirect costs; patients undergoing more than one intervention accrued €2,605 in direct costs and €2,432 in indirect costs.ConclusionsThe economic burden on German statutory health insurance funds and society induced by surgical interventions and related diagnostic procedures for grade 2/3 vulvar and vaginal neoplasia should not be underrated. The cost burden is one part of the overall burden attributable to human papillomavirus infections.

【 授权许可】

Unknown   
© Hampl et al; licensee BioMed Central Ltd. 2011. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.