Hepatoid adenocarcinoma of the gallbladder

World Journal of Surgical Oncology

Case Report

Amouri Ali¹  Sameh Ellouze²  Kossentini Mariem²  Charfi Slim²  Gouiaa Naourez²  Mnif Héla²  Boudawara Tahia²  Guirat Ahmad³  Ben Amar Mohamed³ 

[1] Department of gastroenterology, Hedi Chaker hospital, road El Ain., 3029, Sfax, Tunisia;Department of pathology, Habib Bourguiba Hospital, road El Ain., 3029, Sfax, Tunisia;Department of surgery, Habib Bourguiba hospital, road El Ain., 3029, Sfax, Tunisia;

关键词: Hepatoid;    adenocarcinoma;    gallbladder;    histopathology;    liver;    hepathocellular carcinoma;   

DOI  :  10.1186/1477-7819-9-103

 received in 2011-01-30, accepted in 2011-09-13,  发布年份 2011

来源: Springer

【 摘 要 】

Hepatoid adenocarcinoma is a rare variant of extrahepatic adenocarcinoma which behaves like hepatocellular carcinoma in morphology and functionality.We present a rare case of hepatoid adenocarcinoma of the gallbladder which invades deeply the liver bed, in a 59-year-old woman. Histologically, most of the mass in the gallbladder was composed of cells with eosinophilic cytoplasm arranged in a trabecular pattern, which resembled hepatocellular carcinoma. The main differential diagnosis was hepatocellular carcinoma with invasion into the gallbladder. The gallbladder origin of the hepatoid adenocarcinoma was verified by the presence of foci of conventional adenocarcinoma, the recognition of high-grade dysplasia in the adjacent epithelium and the absence of cirrhosis.

【 授权许可】

Unknown   
© Sameh et al; licensee BioMed Central Ltd. 2011. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.