Self-sampling in cervical cancer screening: comparison of a brush-based and a lavage-based cervicovaginal self-sampling device

BMC Cancer

Research Article

Pekka Nieminen¹  Liisa Karjalainen²  Ahti Anttila²  Tapio Luostarinen²  Anni Virtanen² 

[1] Department of Obstetrics and Gynaecology, Helsinki University Central Hospital, Jorvi Hospital, Turuntie 150, Espoo, Finland;Mass Screening Registry, Finnish Cancer Registry, Unioninkatu 22, FI-00130, Helsinki, Finland;

关键词: Cervical cancer screening;    HPV;    Self-sampling;    Socio-demographic factors;    Acceptability;   

DOI  :  10.1186/s12885-016-2246-9

 received in 2015-08-31, accepted in 2016-03-02,  发布年份 2016

来源: Springer

【 摘 要 】

BackgroundHigh coverage and attendance is essential for cervical cancer screening success. We investigated whether the previous positive experiences on increasing screening attendance by self-sampling in Finland are sampler device dependent.MethodsAll women identified to cervical cancer screening in 2013 in 28 Finnish municipalities were randomised to receive a lavage- (n = 6030) or a brush type of self-sampling device (n = 6045) in case of non-attendance after two invitation letters. Seven hundred seventy non-attending women in the lavage device group and 734 in the brush group received the self-sampling offer. Women’s experiences were enquired with an enclosed questionnaire.ResultsTotal attendance in the lavage group increased from 71.0 to 77.7 % by reminder letters and further to 80.5 % by self-sampling. Respective increase in the brush group was from 72.2 to 78.6 % and then to 81.5 %. The participation by self-sampling was 21.7 % (95 % CI 18.8–24.6) in the lavage group and 23.8 % (95 % CI 20.8–26.9) in the brush group. Women’s self-sampling experiences were mainly positive and the sampler devices were equally well accepted by the women.ConclusionOur study shows that the lavage device and brush device perform similarly in terms of uptake by non-attending women and user comfort. If self-sampling is integrated to the routine screening program in Finland, either of the devices can be chosen without the fear of losing participants due to a less acceptable device.

【 授权许可】

CC BY   
© Karjalainen et al. 2016