Prevalence of suspected hypertrophic cardiomyopathy or left ventricular hypertrophy based on race and gender in teenagers using screening echocardiography

Cardiovascular Ultrasound

Research

Sharon Bates¹  Sudhakar Sattur²  Deborah Strootman²  Mohammad Reza Movahed³ 

[1] Anthony Bates Foundation, 428 E. Thunderbird, #633, 85022, Phoenix, AZ, USA;Sarver Heart Center, Department of Medicine, Division of Cardiology, University of Arizona College of Medicine, 1501 N Campbell Avenue, Tucson, Arizona, USA;Sarver Heart Center, Department of Medicine, Division of Cardiology, University of Arizona College of Medicine, 1501 N Campbell Avenue, Tucson, Arizona, USA;Department of Medicine, Division of Cardiology, The Southern Arizona VA Health Care System, Cardiology (1-111C), 3601 South Sixth Avenue, 85723, Tucson, AZ, USA;

关键词: Left Ventricular Hypertrophy;    African American Population;    African American Race;    Left Ventricular Size;    African American Subject;   

DOI  :  10.1186/1476-7120-8-54

 received in 2010-10-14, accepted in 2010-12-10,  发布年份 2010

来源: Springer

【 摘 要 】

BackgroundThe goal of this study was to evaluate the prevalence of suspected hypertrophic cardiomyopathy (HCM) in a population of teenagers undergoing screening echocardiography for the detection of HCM.MethodThe Anthony Bates Foundation performs screening echocardiography for the prevention of sudden death. A total of 2,066 students were studied between the ages of 13 to 19 years. Suspected HCM was defined as any wall thickness ≥ 15 mm. LVH was defined as wall thickness ≥ 13 mmResultsPrevalence of suspected HCM was 0.7% (14/2066). After adjusting for hypertension (HTN), the total prevalence was 0.5% (8/1457). In a subgroup analysis, 551 teenagers with documented race and LV wall thickness were identified between the ages of 13 - 19 years. African American teenagers [6% (3/50)] had higher prevalence of suspected HCM [0.8% (4/501), OR 7.93, CI 1.72-36.49, p = 0.002]. After multivariate adjustment for age, gender, BMI and HTN (systolic BP >140 and diastolic BP of > 90), African American race remained independently associated with suspected HCM (OR 4.89, CI 1.24-39.62, p = 0.02).ConclusionThe prevalence of suspected HCM in young teenagers is approximately 0.2%. This prevalence appears to be higher in African Americans. However, due to small number of African Americans in our population, our result needs to be confirmed in larger trials.

【 授权许可】

CC BY   
© Movahed et al; licensee BioMed Central Ltd. 2010. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.